We have been studying a protein from southern copperhead snake venom possessing potent anti-tumor activity that we call contortrostatin.
Contortrostatin (CN) is a member of a family of peptides called disintegrins that are found in snake venoms. Members of this family are distinguished by the presence of an amino acid sequence, arginine-glycine-aspartic acid (RGD), that enables them to bind to cell surface receptors called integrins found on cancer cells and newly growing (angiogenic) blood vessels in the tumor. Integrins mediate interactions between cells and their surroundings, and on cancer cells they play important roles in tumor invasion and dissemination.
Markland and his team, studying mice with implanted breast cancer, discovered that contortrostatin prevented the cancer from spreading to the lungs of the mice by 90%.
Snake venoms, particularly those from North American pit vipers, contain direct-acting fibrinolytic proteinases (11).
Cancer death rates are continuing to fall, dropping by 1.8 percent per year in men and 1.6 percent per year in women between 2004 and 2008, according to the American Cancer Society's annual report on cancer statistics released on Wednesday.
Despite improvements in the most common cancers, a companion report found an increase in cases of several cancers over the past decade.
Information has been published in medical journals for almost a decade, about the cancer-fighting properties of the Southern Copperheads venom. A protein in the venom called contortrostatin (CN) causes a disruption in the tumor cell's ability to adhere to and invade neighbor cells while also inhibiting the development of new blood vessels required to sustain the tumor."CN belongs to a class of proteins known as disintegrins, called that because they disrupt the function of certain other proteins, called integrins, on the surface of cells. Integrins are involved in the adhesive phenomenon of cells. CN is effective in retarding the spread of tumor cells because it inhibits their adhesion to and invasion of normal cells in the surrounding tissue. "
Cuban scientists have verified that the toxin in the venom of the Rophalorus junceus scorpion has an analgesic, anti-inflammatory and anti-tumoral effect.
Because this natural and alternative cancer treatment based on the blue scorpion venom, , has achieved amazing results without causing the side effects of conventional treatments.
"Right now it is difficult for a surgeon to be able to distinguish a brain tumor from the normal brain tissue around it," says Dr. James Olson of the Fred Hutchinson Cancer Research Center. He says that this situation often presents today's brain surgeon with an unenviable decision: choose either to cut aggressively, potentially damaging healthy brain tissue, or cut conservatively and run the risk of leaving tumor cells behind.
Enter T-601, the synthetic version of a chemical first found in the scorpion's sting.
For the scorpion, this property if its venom ensures a quick kill of its unfortunate prey. But subtract the poisonous components from the venom, and you have a perfect vehicle for penetrating the brain.
What's more, researchers have found that this chemical seeks out and binds to brain tumor cells.
Patients could safely return home several hours after the procedure, according to Jackson, and their families would be exposed to no more radiation than is typical with a thyroid cancer patient going home after treatment. Patients showed no evidence of adverse reactions, Jackson reports, adding that 54 patients nationwide are currently in investigational trials for the therapy.
Niurys Monzon, 28, says she is a living proof that it works."I was eleven when I was diagnosed," she said, "and started taking Escozul when I was fifteen."
Her father, Jose Felipe Monzon told CNN that in 1992 her cancer of the pancreas had spread despite two years of chemotherapy, radiation treatment and three operations and that doctors had given up.
In desperation, he turned to a man named Misael Bordier, a biologist from Guantanamo who was experimenting with scorpion venom on cancerous tumors in rats and dogs.
Duane has a malignant glioma, a brain tumor that kills 98% of those who get it. After surgery, radiation, and chemotherapy failed, Duane learned of a new treatment using scorpion venom.
So far, 8 patients have undergone the experimental treatment at City of Hope and the University of Alabama in Birmingham. All but one of the patients are still alive.
This documentary explains the Rockefeller influence on the health care industry, and particularly how safe alternatives have been silenced in favor of chemotherapy, radiation and surgery. Going back to the early twentieth century, this movie explains how it all got started, and why we are in our current health care predicament. It then provides cures for those suffering with cancer.
Nontraditional cancer treatments virtually unheard of. Why?