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Originally posted by MrXYZ
Originally posted by TheJackelantern
oops wrong thread..edit on 25-7-2012 by TheJackelantern because: deleted response in wrong thread.
They're very similar
Originally posted by flyingfish
Originally posted by MrXYZ
Originally posted by TheJackelantern
oops wrong thread..edit on 25-7-2012 by TheJackelantern because: deleted response in wrong thread.
They're very similar
Yep...business as usual.
The last one is just for comic affect
There certainly was and is..
Giving a conscious mind can't exist without "CAUSE", yes existence itself did all the work by itself and for itself. Existence creates us, and we being of existence can go on to create other things. At the end of the day, Existence itself is the first cause, and the totality of causality to which governs everything including the conscious state.
After reading your post and the links you've provided - you struck me as a deep thinker if not a philosopher. Unfortunately I don't have that much tolerance with philosophy nor have the heart to discuss philosophy.
If so is the CAUSE intelligent?
And who is this INTELLIGENT first CAUSE?
Is this INTELLIGENT CAUSE according to your philosophy - Existence?
If so - what is existence in scientific terms?
Is it an entity or just a force?
Giving a conscious mind can't exist without "CAUSE", yes existence itself did all the work by itself and for itself. Existence creates us, and we being of existence can go on to create other things. At the end of the day, Existence itself is the first cause, and the totality of causality to which governs everything including the conscious state.
What is GOD without Existence?
Originally posted by edmc^2
reply to post by flyingfish
Now so as to redeem yourself from further embarrassment and show that you have at least an once of intelligence let me please post this question to you also:
If the apparatus used in the Urey-Miller experiment (that produced the non-living organic materials) correspond to the Earth's primitive atmosphere, and the organic materials correspond to the building blocks for life, whom do the scientists - Miller/Urey, et al correspond to in the abiogenesis hypothesis world?
Blind Chance Event or Intelligence?
Don't know?
E = Existence = Energy = information = force = cause = emergent properties = you, me, the stars, and everything else.
Or:
E = Existence
E = Energy
E = Everywhere
E = Emergence or Emerging properties
E = MC^2
E = Evolution
E = Everything
E = Everyone
E = Me to
And if you like, E = easy to understand without having to go into Everything E can do, or how E does Everything it can do. E is thus the only Established and Empirically supported truth we have thus far. E Enables us to do the things we do, and be who we are. And without E there is nothing, no Existence, no me, no you, not anything. And well, it's good to know that E exists simply because nothing can't. It's good to know that E can neither be created nor destroyed. This means we will Exist in some form or another regardless of what happens after death. E is even every letter in the alphabet since it is the Energy that makes up the very Essence of Every letter.
E Explains itself and is self-Explanatory.. It's also Eternal, and gives us the ability to Even have Emotion..
It's simply "E"
Yep, it's simply E if you really want to break it all down into it's simplest form. Now if you like, as stated before, I can describe how this works in relation to a conscious state and time, or the inertia of information in regards to why we know consciousness can't exist without cause.
Physical Sciences: Chemistry
G. W. Hodgson and
Cyril Ponnamperuma
PREBIOTIC PORPHYRIN GENESIS: PORPHYRINS FROM ELECTRIC DISCHARGE IN METHANE, AMMONIA, AND WATER VAPOR PNAS 1968 59 (1) 22-28
...probable synthesis during chemical evolution," Nature, 202, 1231-1232 (1964). 9 Hodgson, G. W., and B. C. Baker, "Porphyrin abiogenesis from pyrrole and formaldehyde under simulated geochemical conditions," Nature, 216, 29-32 (1967). 10 Krashnovskii, A. A...
Dr. Ratcliff and his adviser, Michael Travisano, are experts in experimental evolution. They design experiments in which microbes can evolve interesting new traits within weeks.
“We were sitting in his office drinking coffee, talking about what would be the coolest thing you could do in the lab,” Dr. Ratcliff said. “O.K., the origin of life would be too hard. But other than the origin of life, what would be the coolest thing?” They decided it would be observing single-celled microbes evolving a primitive form of multicellularity.
Electromagnetism is responsible for practically all the phenomena encountered in daily life, with the exception of gravity. Ordinary matter takes its form as a result of en.wikipedia.org... intermolecular forces between individual molecules in matter. Electromagnetism is also the force which holds electrons and protons together inside atoms, which are the building blocks of molecules. This governs the processes involved in chemistry, which arise from interactions between the electrons inside and between atoms.
Why don't they manufacture this theorized self-replicating peptide and prove that it can self replicate. Then we will all know that a self replicating peptide can be ONLY 32 amino acids long.
staff.science.nus.edu.sg...
A Self-Replicating Peptide under Ionic Control
File Format: PDF/Adobe Acrobat - Quick View
by S Yao - Cited by 36 - Related articles
This work was supported by the National Science Foundation. (9457372-CHE). ... K1K2 peptide would self-replicate from smaller fragments only under those .... time makes such coupling reactions possible in an unusually efficient manner.
A pH-Modulated, Self-Replicating Peptide
www.google.com... _papers%2Fdesign5.pdf&ei=LMowT77RFsn20gHi9-X5Bw&usg=AFQjCNFrIhgnANFuixa7A6fYrgtYKSsL6g
File Format: PDF/Adobe Acrobat - Quick View
by S Yao - 1996 - Cited by 58 - Related articles
A pH-Modulated, Self-Replicating Peptide. Shao Yao, Indraneel Ghosh, Reena Zutshi, and. Jean Chmielewski*. Department of Chemistry, Purdue UniVersity ...
A Self-Replicating Peptide Nucleic Acid
Tobias A. Plöger, Günter von Kiedrowski
(Submitted on 21 Dec 2011)
We report on a case of autocatalytic feedback in a template directed synthesis of a self-complementary hexa-PNA from two trimeric building blocks. The course of the reaction was monitored in the presence of increasing initial concentrations of product by means of RP-HPLC. Kinetic modeling with the SimFit program revealed parabolic growth according to the so-called square-root law. The observed template effect, as well as the rate of the ligation, was significantly influenced by factors like nucleophilic catalysts, pH value, and uncharged co-solvents. Systematic optimization of the reaction conditions allowed us to increase the autocatalytic efficiency of the system by two orders of magnitude.
Comments: 36 pages
Subjects: Molecular Networks (q-bio.MN); Populations and Evolution (q-bio.PE)
Cite as: arXiv:1112.4952v1 [q-bio.MN]
Submission history
From: Tobias Plöger [view email]
[v1] Wed, 21 Dec 2011 08:50:52 GMT (897kb)
Mechanosensitive Self-Replication Driven by Self-Organization
www.sciencemag.org...
Jacqui M. A. Carnall1,
Christopher A. Waudby1,2,
Ana M. Belenguer1,
Marc C. A. Stuart3,4,
Jérôme J.-P. Peyralans4 and
Sijbren Otto4,*
+ Author Affiliations
1University of Cambridge, Department of Chemistry, Lensfield Road, Cambridge CB2 1EW, UK.
2Department of Structural and Molecular Biology, University College London, London WC1E 6BT, UK.
3Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, Netherlands.
4Centre for Systems Chemistry, Stratingh Institute, University of Groningen, Nijenborgh 4, 9747 AG Groningen, Netherlands.
*To whom correspondence should be addressed. E-mail: [email protected].
Abstract
We report here two self-replicating peptide-derived macrocycles that emerge from a small dynamic combinatorial library and compete for a common feedstock. Replication is driven by nanostructure formation, resulting from the assembly of the peptides into fibers held together by β sheets. Which of the two replicators becomes dominant is influenced by whether the sample is shaken or stirred. These results establish that mechanical forces can act as a selection pressure in the competition between replicators and can determine the outcome of a covalent synthesis.
Biological Sciences - Biochemistry
www.pnas.org... f+html?sid=e8e56014-5b53-4b56-92...
Arthur L. Weber and
Sandra Pizzarello
The peptide-catalyzed stereospecific synthesis of tetroses: A possible model for prebiotic molecular evolution PNAS 2006 103 (34) 12713-12717; published ahead of print August 11, 2006, doi:10.1073/pnas.0602320103
...facile reaction between amino acids and carbonyl sulfide near volcanic sources ( 25 ). On the other hand...in the distribution of homochiral and racemic peptide products. For homochiral...this end, the l -ee of meteoritic amino acids, which were validated unequivocally...therein). Materials and Methods Peptides and other chemicals were obtained...nitrogen atoms of the peptide catalyst and the C1 of one glycolaldehyde molecule...material, such as the nonracemic amino acids found in meteorites, could have...stereospecific catalysis. Because peptides might have formed readily on the...Biogenesis Catalysis Evolution, Molecular Gas Chromatography-Mass Spectrometry...
Peptides by activation of amino acids with CO on (Ni, Fe) S surfaces: implications for the origin of life
[PDF] from forth.gr
www.sciencemag.org...
C Huber… - Science, 1998 - sciencemag.org... In experiments modeling volcanic or hydrothermal settings amino acids were converted into their peptides by use of coprecipitated ... 1 mmol of NiS in 10 ml of water with 4 mmol of CO gas (1 bar ...CO-SCH 3 ), and by the formation of small amounts of the N-acetyl-amino acids in our ...Cited by 295 - Related articles - BL Direct - All 13 versions
From the prebiotic synthesis of α-amino acids towards a primitive translation apparatus for the synthesis of peptides
www.springerlink.com...
R Pascal, L Boiteau… - Prebiotic Chemistry, 2005 - Springer... atmosphere some local environments may remain favorable to prebiotic chemistry, such as
volcanic plumes or ... Kobayashi and co-workers succeeded in syn- thesizing amino acid precursors(amino acids being observed after acidic hydrolysis) in the gas phase (80 ◦ C..
A sulfurous start for protein synthesis
www.sciencemag.org...
G Vogel - Science, 1998 - sciencemag.org
... The amino acids had to be kept dry, for instance, or be activated by compounds not found in nature. In contrast, Wächtershäuser says, his system “uses nothing more than what is available in volcanic exhalations”—the magma and pressurized gases that suddenly hit cooler .
Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide
pubs.acs.org...
LJ Leman, LE Orgel… - Journal of the American …, 2006 - ACS Publications
... The studies reported here suggest that COS, a simple volcanic gas, could have mediated both ...Citation data is made available by participants in CrossRef's Cited-by Linking service. ... mechanisms and free energetics underlying the formation of peptides from α-amino acids and α
[PDF] Life's first scalding steps
[PDF] from sciencenews.org
www.sciencenews.org...
S Simpson - Science News, 1999 - sciencenews.org... Water and Volcanic Gases Pyruvic Acid Alanine Activated Acetic Acid ... He sees no reason why amino acids simmering in pools of water on rocky shorelines couldn't link up through ... around for the origin of life would like to discover the first molecule that learned to make copies of
Direct asymmetric intermolecular aldol reactions catalyzed by amino acids and small peptides A Córdova, W Zou, P Dziedzic… - …
A European Journal, 2006 - Wiley Online Library...
Get PDF (261K)
onlinelibrary.wiley.com...
Oligopeptide formation may thus have played a role in the evolution of homochirality of sugars. For instance, we found that ancient amino acids that are oligomerized to peptides with the help of volcanic gas20 catalyze the asymmetric
Originally posted by Barcs
Originally posted by totallackey
reply to post by Barcs
Science has CONCLUSIVELY eliminated abiogenesis. finished, kaput, bupkus, nada, (i.e., THAT DOG DOES NOT HUNT!!! STICK A FORK IN IT!!!)
Really? You got a link on that or you just making stuff up again? Last I checked, they were able to duplicate 2 or 3 parts of the process.
Yeah, the link is this...You set a sterile empty box on the table...put a dead mouse in brown paper sack...whirl the brown paper sack over your head and scream like a chicken...check the sterile empty box for signs of life...Repeat the process ad infinitum...Meanwhile, take time to enlist young scientists, gullible enough to carry on your life's work...Have them sign a commitment and utilize a will to provide the exact instruction set...
The only life that will be present at the end of this process is you...until you die...then it will be the sap who takes your place...
The idea that life spontaneously generates from NOTHING came from an IDIOT who observed maggots...So have at it there..
What we have here is an excellent example of a bully who finally meet his/her match and can't respond intelligently, thus he/she is reduced to just ridicule. In other words all the huffing and puffing are nothing but smoke screen and reveals the weakness of his/her argument if there ever was one. So may I suggest to study up more so that you can at least offer a grown up reply instead of the childish reply above. That is of course if you're able think intelligently as 5th grader. tata...
Originally posted by totallackey
Originally posted by Barcs
Originally posted by totallackey
reply to post by Barcs
Science has CONCLUSIVELY eliminated abiogenesis. finished, kaput, bupkus, nada, (i.e., THAT DOG DOES NOT HUNT!!! STICK A FORK IN IT!!!)
Really? You got a link on that or you just making stuff up again? Last I checked, they were able to duplicate 2 or 3 parts of the process.
Yeah, the link is this...You set a sterile empty box on the table...put a dead mouse in brown paper sack...whirl the brown paper sack over your head and scream like a chicken...check the sterile empty box for signs of life...Repeat the process ad infinitum...Meanwhile, take time to enlist young scientists, gullible enough to carry on your life's work...Have them sign a commitment and utilize a will to provide the exact instruction set...
The only life that will be present at the end of this process is you...until you die...then it will be the sap who takes your place...
The idea that life spontaneously generates from NOTHING came from an IDIOT who observed maggots...So have at it there...
Originally posted by flyingfish
reply to post by edmc^2
I'm not going to argue semantics.
All you have done is proved my point.
You cover all the above in this post.
What we have here is an excellent example of a bully who finally meet his/her match and can't respond intelligently, thus he/she is reduced to just ridicule. In other words all the huffing and puffing are nothing but smoke screen and reveals the weakness of his/her argument if there ever was one. So may I suggest to study up more so that you can at least offer a grown up reply instead of the childish reply above. That is of course if you're able think intelligently as 5th grader. tata...
You have received excellent intelligent responses, all you do is argue semantics and common fallacies.
If you can come up with something worth debating I will entertain you.
Ta da.
excellent intelligent responses
you mean the "I Don't Know - We Don't Know" responses? you mean your ridiculous pathetic responses? These are the what you call "excellent intelligent responses"? If so, then you got nothing substantial to offer. Why you can't even answer a simple question: who are the Intelligent people correspond to in the abiogenesis world? No wonder your only response is a childish ridicule. Like I said - study up more before you engage in a adult conversation, maybe by then you can present your side intelligently. tata...
study up more before you engage in a adult conversation
So every time you want to use the "intelligence argument", I will simply point you to learn your ABC's, and to learn energy =/= information as cause of causation:
www.abovetopsecret.com...
www.abovetopsecret.com...
you mean the "I Don't Know - We Don't Know" responses?
you mean your ridiculous pathetic responses?
Like I said - study up more before you engage in a adult conversation, maybe by then you can present your side intelligently.
Originally posted by TheJackelantern
you mean the "I Don't Know - We Don't Know" responses? you mean your ridiculous pathetic responses? These are the what you call "excellent intelligent responses"? If so, then you got nothing substantial to offer. Why you can't even answer a simple question: who are the Intelligent people correspond to in the abiogenesis world? No wonder your only response is a childish ridicule. Like I said - study up more before you engage in a adult conversation, maybe by then you can present your side intelligently. tata...
So you can't answer my questions, especially the one asking you what is god without existence, or especially when you can't seem to engage in any sort of intellectually honest discourse. Hell, you can't even seem to provide academic level material, arguments, or empirical evidence to back yourself up. And you clearly are avoiding at all costs of having to do so. You're basically intellectually bankrupt and you are trying to withdraw funds from an account that is in the red. Worst yet, your question was answered, and the question you are resting your entire argument on is laughable at best as it's not even relevant. And then you complain by appeal to emotion about childish ridicule when you get proved wrong, or when you are unable to cope with being intellectually owned in a discussion that is clearly above your head. And this is a precious statement:
study up more before you engage in a adult conversation
The irony of that statement is incredible to say the least. Here is the total value of all your posts on an academic level: 0
It's pretty funny how that 0 is the same shape of your level of intellectual integrity, honesty, and form of argument to which is nothing but circular. Hence, you have zero relevance in this discussion thus far, and we are wonder when you will actually learn how to be relevant in a discussion. So here we GO, and I am going to do as I promised:
So every time you want to use the "intelligence argument", I will simply point you to learn your ABC's, and to learn energy =/= information as cause of causation:
www.abovetopsecret.com...
www.abovetopsecret.com...
When you can start there, learn the basics, then you might just graduate to a more meaningful and relevant position in this discussion. And here is a good video on advice when getting owned in a debate you clearly have lost:
How to lose an argument and win:
www.youtube.com...
edit on 26-7-2012 by TheJackelantern because: (no reason given)edit on 26-7-2012 by TheJackelantern because: (no reason given)
So you can't answer my questions, especially the one asking you what is god without existence, or especially when you can't seem to engage in any sort of intellectually honest discourse.
have zero relevance in this discussion thus far, and we are wonder when you will actually learn how to be relevant in a discussion.
Well, it's the only true answer given that we DON'T KNOW...so calling it "pathetic" is incredibly silly
Originally posted by flyingfish
Originally posted by MrXYZ
Originally posted by TheJackelantern
oops wrong thread..edit on 25-7-2012 by TheJackelantern because: deleted response in wrong thread.
They're very similar
Yep...business as usual.
The last one is just for comic affect
Originally posted by TheJackelantern
And some Primary source material:
Arthur L. Weber and
Sandra Pizzarello
The peptide-catalyzed stereospecific synthesis of tetroses: A possible model for prebiotic molecular evolution
...facile reaction between amino acids and carbonyl sulfide near volcanic sources ( 25 ). On the other hand...in the distribution of homochiral and racemic peptide products. For homochiral...this end, the l -ee of meteoritic amino acids, which were validated unequivocally...therein). Materials and Methods Peptides and other chemicals were obtained...nitrogen atoms of the peptide catalyst and the C1 of one glycolaldehyde molecule...material, such as the nonracemic amino acids found in meteorites, could have...stereospecific catalysis. Because peptides might have formed readily on the...Biogenesis Catalysis Evolution, Molecular Gas Chromatography-Mass Spectrometry...
Peptides by activation of amino acids with CO on (Ni, Fe) S surfaces: implications for the origin of life
[PDF] from forth.gr
C Huber… - Science, 1998 - sciencemag.org... In experiments modeling volcanic or hydrothermal settings amino acids were converted into their peptides by use of coprecipitated ... 1 mmol of NiS in 10 ml of water with 4 mmol of CO gas (1 bar ...CO-SCH 3 ), and by the formation of small amounts of the N-acetyl-amino acids in our ...Cited by 295 - Related articles - BL Direct - All 13 versions
From the prebiotic synthesis of α-amino acids towards a primitive translation apparatus for the synthesis of peptides
R Pascal, L Boiteau… - Prebiotic Chemistry, 2005 - Springer... atmosphere some local environments may remain favorable to prebiotic chemistry, such as
volcanic plumes or ... Kobayashi and co-workers succeeded in syn- thesizing amino acid precursors(amino acids being observed after acidic hydrolysis) in the gas phase (80 ◦ C..
A sulfurous start for protein synthesis
G Vogel - Science, 1998 - sciencemag.org
... The amino acids had to be kept dry, for instance, or be activated by compounds not found in nature. In contrast, Wächtershäuser says, his system “uses nothing more than what is available in volcanic exhalations”—the magma and pressurized gases that suddenly hit cooler .
Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide
LJ Leman, LE Orgel… - Journal of the American …, 2006 - ACS Publications
... The studies reported here suggest that COS, a simple volcanic gas, could have mediated both ...Citation data is made available by participants in CrossRef's Cited-by Linking service. ... mechanisms and free energetics underlying the formation of peptides from α-amino acids and α
S Simpson - Science News, 1999 - sciencenews.org... Water and Volcanic Gases Pyruvic Acid Alanine Activated Acetic Acid ... He sees no reason why amino acids simmering in pools of water on rocky shorelines couldn't link up through ... around for the origin of life would like to discover the first molecule that learned to make copies of
Direct asymmetric intermolecular aldol reactions catalyzed by amino acids and small peptides A Córdova, W Zou, P Dziedzic… - …
Oligopeptide formation may thus have played a role in the evolution of homochirality of sugars. For instance, we found that ancient amino acids that are oligomerized to peptides with the help of volcanic gas20 catalyze the asymmetric
Oligopeptide formation may thus have played a role in the evolution of homochirality of sugars. For instance, we found that ancient amino acids that are oligomerized to peptides with the help of volcanic gas20 catalyze the asymmetric