Pharmaceutical company Merck announced today they were discontinuing production and sale of the wildly popular arthritis medicin Vioxx. Clinical
testing 5 years after the drug entered the market showed it doubled a patient's risk of heart attack, stroke, and other cardiovascular conditions.
Vioxx is taken by millions of arthritis sufferers around the world to ease their pain, and was also believed to be a key drug in preventing some
cancers.
Forbes.com
Merck said Thursday that data from the trial showed the increased risk of heart attack and other cardiovascular complications began 18 months after
patients started taking Vioxx. About 2 million people worldwide are currently taking Vioxx, according to Merck, and a total of 84 million have taken
it since it came on the market with great fanfare in 1999.
The data comes from a three-year study aimed at showing that Vioxx at a 25 milligram dose prevents recurrence of polyps in the colon and rectum. Such
polyps can turn cancerous. The trial was stopped after Merck discovered study participants had double the risk of a heart attack compared to other
participants taking dummy pills.
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Merck has not commented as to why these heath risks were not discovered during pre-released clinical trials. Shares of the company's stock plummeted
on news of the discontinuation.
[edit on 30-9-2004 by Banshee]