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In 1986, Scott's micro-manufacturer and distributor of Botox was no longer able to supply the drug because of an inability to obtain product liability insurance. Patients became desperate as supplies of Botox were gradually consumed, forcing him to abandon patients who would have been due for their next injection. For a period of four months, American blepharospasm patients had to arrange to have their injections performed by participating doctors at Canadian eye centers until the liability issues could be resolved.
The big difference between marijuana and hemp is the production of different chemicals called cannabinoids. Marijuana produces tetrahydrocannabinolic acid (THCA, which turns into THC when heated) instead of the non-psychoactive compound cannabidiolic acid produced by the hemp plant strains. THCA is the compound that is responsible for not only the high that pot gives, but also its medicinal effects. To figure out why one strain produces THCA and the other doesn't, Page and Tim Hughes, of the University of Toronto, analyzed the complete genetic codes, or genomes, of the marijuana strain Purple Kush (widely used for medicinal purposes) and the domesticated hemp strain called Finola.