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i have been a long time reader and had to become a member after reading this thread.
One cautionary tale about the perils of relying on a homogenous food source revolves around the humble potato. High in the Peruvian Andes, where the potato was first domesticated, farmers still grow thousands of otherworldly looking varieties. Spanish ships in the late 16th century first brought the tuber to Europe, where by the early 1800s it had become a reliable backup to cereal crops...
The effect of a semipurified root extract of W. somnifera containing mostly withanolides was investigated using a transgenic mouse model of Alzheimer's disease. The transgenic mice showed reversal of behavioral deficits and plaque load after treatment with the extract for 30 days.