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For roughly two thousand years, Chinese herbalists have treated Malaria using a root extract, commonly known as Chang Shan, from a type of hydrangea that grows in Tibet and Nepal. More recent studies suggest that halofuginone, a compound derived from this extract's bioactive ingredient, could be used to treat many autoimmune disorders as well. Now, researchers from the Harvard School of Dental Medicine have discovered the molecular secrets behind this herbal extract's power.
It turns out that halofuginone (HF) triggers a stress-response pathway that blocks the development of a harmful class of immune cells, called Th17 cells, which have been implicated in many autoimmune disorders.
"HF prevents the autoimmune response without dampening immunity altogether," said Malcolm Whitman, a professor of developmental biology at Harvard School of Dental Medicine and senior author on the new study. "This compound could inspire novel therapeutic approaches to a variety of autoimmune disorders."
"This study is an exciting example of how solving the molecular mechanism of traditional herbal medicine can lead both to new insights into physiological regulation and to novel approaches to the treatment of disease," said Tracy Keller, an instructor in Whitman's lab and the first author on the paper.
I was diagnosed with a small case of tonsillitis a few months ago and my internist recommended I go on anti-biotics; I said I prefer not to and declined the prescription. I started taking Ester-C 1000mg and Oregano buffered 500mg daily with my several other supplements....In 5 days, my fever and swelling of my tonsils were gone, I swear. My internist was impressed and asked if I had any interest in alternative medicine, and I currently attend Stony Brook university so anything is possible in the realms of medicine.
Thanks for the interesting article and your interest in alternative medicine
Welcome to the corporate containment of ancient medicinal miracles, people. Say good bye to Chinese remedies.