reply to post by Afterthought
Yes, it does go through the system rapidly, but we're not talking about water here. Even though it doesn't stay in the system, it still has the
ability to affect the body in negative ways.
The side effects are 'on-target', that is, they are dose related. Beta agonists, like ractopamine, can cause an increase in heart rate and/or
relaxation of smooth muscle depending on what receptor they are selective for. Adrenaline (epinephrine) is an example of a beta agonist; salbutamol
(used to treat asthma) is another one.
If you understand the actual mechanism(s) behind how a certain drug causes side effects it makes it a whole lot less scary (fear of the unknown and
all that)
NB, I am not saying that ractopamine is safe and that the side effects are nothing to worry about, because if it was truly safe then it it wouldn't be
banned in several countries. I'm just saying that from knowing how drugs work and how they exhibit their (side) effect it makes them sort of less
daunting (I'm don't really know if that makes any sense, probably not)
Just as acetominophen exits the body quickly, it still has time to make an impact.
Well only if you take too much. If you take a reasonable dose of paracetamol, it is metabolised via glucuronidation and sulphation (if you wanted to
know) if it is metabolised by those two processes then it isn't toxic - paracetamol itself isn't toxic.
It only becomes toxic when you take too much of it, causing the glucuronidation and sulphation pathways to become saturated, forcing it to go down the
CYP450 metabolic route where it is converted into NAPQI which is the toxic chemical responsible for necrosis, hepatitis and/or death when someone has
overdosed.
edit on 26/1/2012 by Griffo because: (no reason given)