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In 2010 the Breast Cancer Fund, a nonprofit group that looks at the scientific evidence linking chemical exposure to breast cancer. In regards to Bisphenol A exposure, the report cites concerns for the development of breast cancer.
Studies using cultures of human breast cancer cells demonstrate that BPA acts through the same response pathways as the natural estrogen estradiol
Plastics and pesticides are examples of products that contain oestrogenic endocrine-disrupting chemicals, or EEDCs, which can interfere with mammalian development by mimicking the action of the sex hormone oestradiol. For instance, the exposure of developing rodents to high doses of EEDCs advances puberty and alters their reproductive function
Several studies using both rat and mouse models have demonstrated that even brief exposures to environmentally relevant doses of BPA during gestation or around the time of birth lead to changes in mammary tissue structure predictive of later development of tumors.
Exposure also increased sensitivity to estrogen at puberty. Recent data demonstrate that early exposure to BPA leads to abnormalities in mammary tissue development that are observable even during gestation and are maintained into adulthood.
Interestingly, some of the long-term effects of neonatal exposure to BPA may be dose dependent, with low- and high-dose exposures resulting in different timing and profiles of changes in mammary gland gene expression.
New research suggests that exposure to bisphenol A (BPA) during gestation and lactation lowers male fertility in adulthood and that the effect may persist for at least three generations. The rat study tested relatively low levels of BPA chosen to fall within the range of human exposures.
In the recent study, data collected from Chinese workers exposed to BPA exhibited a clear connection between even very low levels of BPA and sperm destruction. BPA exposure resulted in a 300 percent increased risk of low sperm concentration and low sperm vitality compared to those not exposed.
Scientists have not determined how much of a receipt's BPA coating can transfer to the skin and from there into the body. Possibilities being explored include:
• Oral exposure -- BPA moves from receipts onto fingers and then onto food and into the mouth.
• Dermal exposure -- BPA from receipts is directly absorbed through the skin into the body.
A study published July 11 by Swiss scientists found that BPA transfers readily from receipts to skin and can penetrate the skin to such a depth that it cannot be washed off. This raises the possibility that the chemical infiltrates the skin's lower layers to enter the bloodstream directly. BPA has also been shown to penetrate skin in laboratory studies.
Laboratory tests found high levels of the estrogen-like chemical bisphenol A on 40% of cash register receipts from major U.S. businesses
An analysis of EWG's tests for BPA contamination in canned food reveals that people who eat canned foods are likely to ingest doses of BPA that are very close to levels now known to harm laboratory animals.
BPA levels higher than those in canned foods, baby bottles and infant formula were detected on at least one of several receipts from Chevron, McDonalds, CVS, KFC, Whole Foods, Safeway, the U.S. Postal Service, Walmart and the U.S. House of Representatives cafeteria, according to the private Washington-based research group.
Consumers can identify products that contain BPA by referring to the numbers in the triangle on the bottom of plastic containers. These SPI Resin Identification Codes are used to identify from which type of plastic a product is made. Resin codes one through six identify particular resins while seven (7) includes all others, including those from BPA, and any combinations of the six.
1 Polyethylene Terephthalate (PET)
2 High Density Polyethylene (HDPE)
3 Polyvinyl Chloride (Vinyl)
4 Low Density Polyethylene (LDPE)
5 Polypropylene (PP)
6 Polystyrene (PS)
Questions and Answers About Bisphenol-A (BPA)
List of the "most" dangerous plastics
??0?? Bisphenol A (7 arrows):
1 Polyvinyl Chloride (PVC) (3 arrows): contains phthalates, which are known to disrupt hormones -- especially testosterone. Congress has banned the use of these chemicals in toys because of research that indicates developmental and reproductive damage.
2 Polystyrene (PS) (6 arrows): This type of plastic can leach styrene into food, especially when heated. Styrene is classified as a possible human carcinogen by the EPA and by the International Agency for Research on Cancer.
??3?? Polycarbonate (PC) and Other (7 arrows): Polycarbonate plastic is the only plastic that is made with bisphenol-A (BPA), which has been found to mimic the hormone estrogen and disrupt the body's endocrine system. Public health advocates say it poses a particular risk to fetuses, infants and children. The National Toxicology Program issued a report last year that includes concerns about BPA's effects on the brain, prostate gland, mammary gland, and behavior in fetuses, infants and children.
4 Polyethylene (PET or PETE) (4 arrows): Used in disposable containers for most bottled water, bottled soft drinks, juice, mouthwash, ketchup, peanut butter, jelly and pickles. Also used in microwavable trays. This plastic is fine for single use. Avoid reusing #1 water and soda bottles because the plastic is porous and these bottles absorb flavors and bacteria that can't be cleaned out.
The only "useable" products is
5 Polyethylene (HDPE or LDPE) (2 and 4 arrows): High Density Polyethylene (HDPE / #2) is a cloudy or opaque plastic used for jugs of milk, water, juice, shampoo and detergent, as well as cereal-box liners. Low Density Polyethylene (LDPE / #4) is used for cling wraps and food storage bags, garbage and grocery bags, squeeze bottles, and coatings for milk cartons and hot-beverage cups.These plastics are generally good choices as they transmit no known chemicals into food and are generally recyclable.
The Most Dangerous Plastics
Originally posted by baddmove
Do they line the inside of beer cans with BPA?
my brand doesn't come in a bottle..
San Francisco, CA, September 12, 2011 – A study published in the Oxford University Press journal, Carcinogenesis, concludes that healthy breast cells exposed to bisphenol-A (BPA) and methylparaben, a common ingredient in beauty products, change from normal and begin to grow and survive like cancer cells. This new research also indicates that BPA exposure may reduce the effectiveness of certain popular and promising breast cancer drugs.
Exposure to the chemicals BPA and methylparaben activates mTOR, a cell’s central mechanism to control cancer growth. When the mTOR signal is turned off, cancer cells do not survive, however, once mTOR is activated, cancer cells can grow and thrive.
“Not every cell exposed to BPA or methylparaben will become cancer, but anything – any chemical exposure – that “flips the switch” and causes healthy cells to act like cancer is cause for concern,” says Dr. William Goodson, lead author and Senior Clinical Research Scientist at California Pacific Medical Center Research Institute.
Dr. Goodson says, “The evidence is strong and getting stronger, that BPA poses a real threat to people, and it’s time to take it out of the food chain.” He continued, “But real change will need the support of everyone. Up to now, industry has avoided having to prove that the chemicals they use are not harmful. This kind of data shifts the responsibility. Industry should now be told to show us that these chemicals are safe.” Bisphenol-A causes normal breast cells to act like cancer
In human fat tissues, bisphenol A (BPA) suppresses levels of a key hormone, adiponectin, that protects people from heart attacks and Type II diabetes. These results implicate BPA as a potential cause of metabolic syndrome, one of the most serious and costly public health problems in the US.
Hugo et al. carried out a series of experiments with fat tissue surgically removed from people, exposing the tissue to different amounts of BPA and observing how this affected adiponectin levels. They compared BPA's effect to that of estradiol (E2), a natural form of human estrogen.
It is important to note that these results were obtained using human tissues and hence avoid the challenges that often arise when extrapolating results from rodents to people.
These results show that BPA at levels well-within the range of common human exposure suppress levels of a hormone that protects people from metabolic syndrome and its consequences: heart disease and Type 2 diabetes. In many of the experiments, BPA's effect was comparable to E2's, and in some even stronger. The effects were seen in all three types of tissues examined.
Diverse and robust data, both prospective and longitudinal, link low adiponectin levels to increased risk of heart attacks and Type 2 diabetes. This link is thought to be causal: Lower adiponectin levels cause heart attacks and Type 2 diabetes. These results thus predict that BPA, by suppressing adiponectin, is a causal agent for these illnesses. Source
High levels of exposure to the chemical bisphenol-A, or BPA as it is commonly known, may increase a person's risk of developing type 2 diabetes, according to a new study.
For the present study, a team of researchers from West Virginia University analyzed urine samples collected between 2003 and 2008 as part of the National Health and Nutrition Examination Survey. The results, which were published in the Journal of Clinical Endocrinology and Metabolism, showed that higher levels of BPA were associated with an increased risk of developing type 2 diabetes.
Furthermore, the researchers said that this association persisted regardless of age, gender, race or body mass index, other factors that may potentially contribute to a person's overall risk of developing type 2 diabetes. Source 2
Recent studies have also shown that this substance stimulated the production of insulin by the pancreas, and would promote the development of adipose tissue, principal place of storage of fat in the body.
Accumulation exaggerated fat in the liver, is not in itself a major gravity character, but the risk of fostering the emergence of other tissue and metabolic alterations.” “And therefore diseases such as type 2 diabetes
As a man ages, his body’s production of testosterone naturally decreases and as a result low testosterone can increase your risk of chronic disease. It can also rob you of your strength and muscularity, your virility, even your drive and ambition. And here’s another slammer hitting most mature men. Not only do we have to contend with naturally declining testosterone levels, we are also affected by increasing levels of estrogens that feminize our bodies. Source