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Fact sheet N°312
█ 346 million people worldwide have diabetes.
█ In 2004, an estimated 3.4 million people died from consequences of high blood sugar. More than 80% of diabetes deaths occur in low- and middle-income countries. WHO projects that diabetes deaths will double between 2005 and 2030. Healthy diet, regular physical activity, maintaining a normal body weight and avoiding tobacco use can prevent or delay the onset of type 2 diabetes.
Richard is host of [removed for TOS] and invests in the junior resource sector. His articles have been published on over 200 websites including: Wall Street Journal, SafeHaven, Market Oracle, USAToday, National Post, Stockhouse, Casey Research, 24hgold, Vancouver Sun, SilverBearCafe, 321Gold, Kitco, Gold-Eagle, The Gold/Energy Reports, Calgary Herald and Financial Sense.
As a general rule, the most successful man in life is the man who has the best information. The foods you eat are broken down into a simple sugar called glucose. In response to a rise in glucose after eating, your pancreas secretes insulin. Insulin moves the glucose from your blood stream into the cells where it can be utilized for energy. Diabetes is a chronic disease that's caused by the pancreas not producing enough insulin, or when the body cannot effectively use the insulin the pancreas produces.
Diabetes is a condition in which normal blood sugar levels are too high. A Type 1 diabetes diagnosis means your pancreatic beta cells that secrete insulin have been damaged or destroyed - glucose cannot move from the bloodstream into the cells. A Type 2 (insulin resistance) diabetes diagnosis is a far more common verdict for people than Type 1. Insulin resistance happens because of chronically elevated blood sugar and insulin. These elevated levels of sugar and insulin have the effect of "numbing" the cellular processes which moves the sugar from the blood stream to the cells - the body cannot respond to the insulin "requests" to move blood sugar into the cells. Roughly 27% of the people who start out as Type 2 diabetics, will, in the future, require insulin injections similar to Type 1 diabetics.
Complications of Diabetes:
█ Diabetic adults are 2 to 4 times more likely to die from heart disease than adults without diabetes
█ Diabetics are 2 to 4 times more likely to suffer a stroke
█ Diabetes is the leading cause for new blindness in adults 20-74 years of age.
█ Diabetes is the leading cause for kidney failure
█ Approximately 60% to 70% of diabetics have some form of nerve damage Over 60% of non-traumatic lower-limb amputations occur in diabetics
█ Dental disease is more common in diabetics
In 1985, there were an estimated 30 million people with diabetes worldwide. Today there are more than 300 million people with diabetes. Within 20 years it is estimated the number of people with diabetes will reach close to 500 million. An estimated 3.8 million people worldwide died from diabetes related causes in 2007. Global health expenditures to treat and prevent diabetes and its complications total at least US$232 billion in 2007. By 2025, this number will exceed US$302 billion. The Standard of Care for patients with reduced or missing critical hormones or proteins, such as insulin, is often monitoring and injecting these proteins multiple times a day. Today's cell transplant technology (an eight billion dollar a year market) promises to provide a solution to the problem of these biochemical deficiencies and a relief from multiple daily injections but, maintaining the transplanted cell population in the recipient has been the major problem. At this time there is no approved device to house and protect transplanted therapeutic cells in the body. But for people suffering biochemical deficiencies such a device might soon become a reality and for diabetics in particular, the first example of Sernova's Cell Pouch System™, an artificial pancreas - a potential natural insulin pump with the added benefit of fine-tuned glucose control - will be in human trials this year.
Important findings reported by Sernova include:
☺ Glucose control was achieved using the Cell Pouch System(tm) at the lowest dose of islets transplanted, about 25% of the islets typically used in other international clinical islet transplantation programs. .
☺ Islet transplanted animals were C-peptide positive, a gold standard measure of islet released insulin glucose control.
☺ Presence of insulin in the islets within the Cell Pouch System(tm) was confirmed by insulin staining. Treated diabetic animals maintained good health including stable body weight confirming the effectiveness of the Cell Pouch System(tm) transplant. No adverse events related to the Cell Pouch System(tm) occurred during the study.
Cell Pouch™ Safety
Device fits inconspicuously under the skin
Implantation is minimally invasive; no exposure of deep tissues
No infection or other safety issues post healing of incision site (n>39)