One of the main differences is it will not run on solar power, which means it can operate continuously at night and more importantly in the shadows of the crater its going to where traces of water or past life are more likely to be revealed. It also has more equipment to penetrate the surface and peer down subsurface to some degree more than before.

It will be the first of the rovers to carry on the tradition on another planet of humans polluting pristine areas with poisonous and radioactive Plutonium.