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Like acetylcholine, nicotine leads to a burst of receptor activity. However, unlike acetylcholine, nicotine is not regulated by your body. While neurons typically release small amounts of acetylcholine in a regulated manner, nicotine activates cholinergic neurons (which mainly use acetylcholine to communicate to other neurons) in many different regions throughout your brain simultaneously. This stimulation leads to:
Increased release of acetylcholine from the neurons, leading to heightened activity in cholinergic pathways throughout your brain. This cholinergic activity calls your body and brain to action, and this is the wake-up call that many smokers use to re-energize themselves throughout the day. Through these pathways, nicotine improves your reaction time and your ability to pay attention, making you feel like you can work better.
Stimulation of cholinergic neurons promotes the release of the neurotransmitter dopamine in the reward pathways of your brain. This neural circuitry is supposed to reinforce behaviors that are essential to your survival, like eating when you're hungry. Stimulating neurons in these areas of the brain brings on pleasant, happy feelings that encourage you to do these things again and again. When drugs like coc aine or nicotine activate the reward pathways, it reinforces your desire to use them again because you feel so at peace and happy afterwards.
Release of glutamate, a neurotransmitter involved in learning and memory - Glutamate enhances the connections between sets of neurons. These stronger connections may be the physical basis of what we know as memory. When you use nicotine, glutamate may create a memory loop of the good feelings you get and further drive the desire to use nicotine.
Nicotine also increases the level of other neurotransmitters and chemicals that modulate how your brain works. For example, your brain makes more endorphins in response to nicotine. Endorphins are small proteins that are often called the body's natural pain killer. It turns out that the chemical structure of endorphins is very similar to that of heavy-duty synthetic painkillers like morphine. Endorphins can lead to feelings of euphoria also. If you're familiar with the runner's high that kicks in during a rigorous race, you've experienced the "endorphin rush." This outpouring of chemicals gives you a mental edge to finish the race while temporarily masking the nagging pains you might otherwise feel.
and quite frankly you can never trust a person that needs a drug to operate.
Originally posted by Frater210
What could possibly not be good about this if you need a boost in high stress environments?
Thanks for the OP.
But they are hardened, if you carry them in the leatherette charging cigarette case accessory.
Originally posted by Talltexxxan
reply to post by Six6Six
Well I guess your just Mr.Perfect then, arnt ya?
Really? wow, just wow!
If this is truly how you feel about someone who has an addiction than maybe you should be the first in line for the gas chambers. Theres alot I would like to say to you but all would be in violation of ATS's T & C.
Geeez...... Love is unconditional brotha, and you need alot of it.
I believe it was a speech made in the movie " The Great Dictator" that it is said.
"Only the unloved hate"edit on 20-10-2011 by Talltexxxan because: (no reason given)
Originally posted by jplaysguitar
reply to post by Six6Six
lol you underestimate smokers! .if you gota a smoker and cigs are running low that dose not make them less effective. If anything thay are even more efective becuas thay will be far more motivated to get out in to town to re up on smokes.
and the whole lumping smokers and the obeese with the likes of pedophiles?? really?
i tried to keep an open mind with you until i read that little gem! haha
Are you shur you are in the right place?
you prolly just alienated more then half the ATS comunityedit on 20-10-2011 by jplaysguitar because: 777
Originally posted by BadNinja68
e-cigs do not use glycerine. They use propylene glycol mixed with liquid nicotine.
The element in the e gic doesnt get hot enough to vaporize glycerine.
PG will work to make your own if you use food grade PG, not the PG used in Humidors.
If yer e cig gets fried, just use a flame to heat a piece of titanium ( other metals give off toxic fumes at low heat levels, Ti doesnt) to about 250 deg F and drop a drop of your e-cig juice and inhale the vapor.
No electricity needed.
I would vote for smokers to be rounded up and be the first in line in the depopulation agenda.
Smokers have long been a useless part of society
I would rather hold the company of a serial killer than that of a room full of smokers.