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Noncommunicable diseases (NCDs) are the leading causes of death globally, killing more people each year than all other causes combined. ….
Of the 57 million deaths that occurred globally in 2008, 36 million – almost two thirds – were due to NCDs, comprising mainly cardiovascular diseases, cancers, diabetes and chronic lung diseases. ....About one fourth of global NCD-related deaths take place before the age of 60.
NCDs have become a universal threat. They kill three in five people a year ...in 2011 ...Roughly a third will be younger than 60. Even larger numbers of people are living disabled by these illnesses.
Chronic disease to cost $47 trillion by 2030: WEF
The global economic impact of the five leading chronic diseases -- cancer, diabetes, mental illness, heart disease, and respiratory disease -- could reach $47 trillion over the next 20 years, according to a study by the World Economic Forum (WEF). ….
"This is not a health issue, this is an economic issue ….." ……
….Mental health, which is typically left off lists of leading NCDs, will account for $16 trillion -- a third of the overall $47 trillion anticipated costs.
U.S. Halts Long-Term Care Program
The Obama administration said Friday it is unable to implement a long-term care insurance program that was part of the 2010 health overhaul, effectively ending the program before it started.
The initiative, known as the Class Act, was included in the law to help Americans cover the cost of aid for daily-living needs such as bathing and using the toilet if they became unable to care for themselves.
Its affordability, the increase in long-term chronic illnesses ….and the ….affordability of elderly social care are used by some to argue for the break-up of the NHS or at least for its fundamental reform.
…..The Government has made it clear that it wants the NHS to be opened up to more competition.
On ATS: NHS Privatisation Day?; NHS Bill clears major Lords hurdles.
The push is in the offing since the Indian Council of Medical Research (ICMR) has recommended to the Union health ministry to make cancer a "notifiable disease".
At present, highly infectious diseases like plague, polio, H5N1 bird flu or the H1N1 swine flu figure in the list. Cancer will become the first non-communicable disease (NCD) to be bracketed under the same category.
On ATS: Cancer to be a "Notifiable Disease" in India
There was a nice older man there in a wheel chair that asked what brought me to the protest, I told him that I was skeptical of OWS and just wanted to see exactly what goes on at one of the protests. He told me ...the government has repeatedly denied him Social Security Disability even after the documentation by his doctor of his serious seizure problems…. At the same time he said that his neighbor is receiving government assistance but is perfectly healthy, the man just complains about his knee, anxiety, and anger issues.
...it has always been accepted that folded protein, not the gene, directly transmits inherited information into biological activity.
…..in the early 1960s, Christian Anfinsen showed that the proteins actually tie themselves: If proteins become un-folded, they fold back into proper shape of their own accord; no shaper or folder is needed. …..Anfinsens investigation of what some call the second genetic code…..
Protein Misfolding Diseases: Current and Emerging Principles and Therapies
'Lifeless' Prion Proteins Are 'Capable of Evolution'
Current laws do not require the systematic screening of chemicals for their ability to cause brain damage or alter brain growth, and only about 20 percent of the 3,000 chemicals produced in high volume in the United States have been tested for developmental toxicity of any kind. The Lancet paper concludes: “The combined evidence suggests that neurodevelopmental disorders caused by industrial chemicals have created a silent pandemic in modern society.”
In the basket of problems labeled neurodevelopmental disorders are a variety of cognitive and psychomotor disabilities. Mental retardation is one. Attention deficit disorder, with or without hyperactivity, is another. A third is learning disabilities, variously characterized by significant difficulties in listening, speaking, writing, memorizing, reading, or calculating. Within the life-altering category of pervasive developmental disorders is autism.
By pandemic, the Lancet study authors mean that developmental disorders are common, cut across all walks of life in all geographic regions, and are ballooning in prevalence. ….By silent, the authors mean that these disorders are subclinical. They don’t announce themselves on an X-ray or in a pathology lab. There is no medical test to herald their increasingly familiar presence among us.
Child neurodevelopmental disorders do, however, leave economic tracks behind. At $77.3 billion per school year, special education and education for disabled students, according to the most recent accounting, consume 19 percent of U.S. school spending.
A Role for Protein Misfolding in Immunogenicity of Biopharmaceuticals
…..misfolding of therapeutic proteins is an immunogenic signal and a risk factor for immunogenicity. ……Over the past decades, the use of therapeutic proteins has become common practice in medicine ……
Protein misfolding is an intrinsic and problematic property of proteins, which underlies a variety of degenerative diseases, such as Alzheimer disease. ….
……biopharmaceuticals, like any other protein, …misfolding… takes place in several preparations.
….. Various Biopharmaceuticals Display Amyloid-like Properties upon Exposure to Conditions of Stress, Indicating Protein Misfolding — During manufacturing and storage, biopharmaceuticals may also become exposed to various conditions of stress that can potentially underlie protein misfolding and the formation of amyloid-like properties.
…….the innate immune system may be activated by recognition of the amyloid-like properties of misfolded protein. …
The controlled self-assembly of complex molecules into well defined hierarchical structures is a promising route for fabricating nanostructures. These nanoscale structures can be realized by naturally occurring proteins such as tobacco mosaic virus, capsid proteins, tubulin, actin, etc.
.....Several cell types found on the human skin, including keratinocytes, fibroblasts and lymphocytes, are susceptible to the abnormal infective isoform of the prion protein, which transforms the skin to produce a potential target for prion infection.
Is Biotech Creating New Incurable Diseases Accidentally?
Even when engineered mutations do not change amino acids, they cause proteins to misfold - which can change the proteins' functions in unexpected ways. Recently released research from the National Cancer Institute in Bethesda, Maryland confirms the misfolding effect, and for the first time, reports finding it in mammals. Misfolded proteins can create incurable diseases, and the phenomenon is causing renewed, but muted concern in the scientific world.
Did Chemical and Drug Industries Create Mad Cow?
What's killing us? Diseases that will kill 9 of 10 Americans
…..cancer, heart disease, diabetes, and a variety of other chronic ailments. And worse, unlike some infectious diseases, they're quite preventable.
This new, ultra-deadly pandemic threat is caused by we, ourselves. Sedentary lifestyles, poor eating habits, smoking, and other high-risk behavior causes most of these diseases. ….
More than anything, the root causes are apathy and sloth.
Originally posted by TheImmaculateD1
Your argument is weak and attacks the little guy who is continuing to be choked out of existence.
Represented by the World Economic Forum (WEF), global corporate interests say the global economic crisis is caused by the chronic disease NCD Pandemic. They say it's sick people who are bankrupting nations, not corporate greed. And even though the evidence shows corporate industry creates the disease agents causing chronic disease, they blame the victims, insisting "people make themselves sick."
Originally posted by doctornamtab
So.....we should protest misfolding proteins?
I have a question-If the cause of these diseases are caused by Prions then why are so many of them eliminated by diet? (I have met many people who regain their health by going Paleo or Vegan.)
New Inhibitors of Scrapie-Associated Prion Protein Formation in a Library of 2,000 Drugs and Natural Products
Several classes of compounds were represented in the 17 most potent inhibitors, including naturally occurring polyphenols (e.g., tannic acid and tea extracts), phenothiazines, antihistamines, statins, and antimalarial compounds. ...many are either approved human drugs or edible natural products...