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I believe every emotional disorder can be overcome, no matter how bad. I was so far off. I remember thinking i would never get better. I am doomed to this life. All it takes is courage, trust in your self and your abilities, in your environment, and ultimately, in G-d.
Proteins are the building blocks of life - and our bodies are constantly creating new ones for repair, maintenance and replacement parts. These proteins don't just need the right chemistry - they need to be folded into exactly the right shape to work. Problem is, proteins misfold easily, in response to "environmental perturbations" - including temperature changes, or exposure to chemicals, heavy metals, oxygen or radiation.
A Role for Protein Misfolding in Immunogenicity of Biopharmaceuticals
…..misfolding of therapeutic proteins is an immunogenic signal and a risk factor for immunogenicity. ……Over the past decades, the use of therapeutic proteins has become common practice in medicine ……
Protein misfolding is an intrinsic and problematic property of proteins, which underlies a variety of degenerative diseases, such as Alzheimer disease. These diseases are characterized by the occurrence of fibrillar deposits, classically termed amyloid, containing aggregates of misfolded proteins.
……experiments pointed out that biopharmaceuticals, like any other protein, are amyloidogenic and that misfolding, detected by amyloid markers, takes place in several preparations. These markers, however, are not necessarily specific for fibrillar amyloid, but also for smaller misfolded protein species.
….. Various Biopharmaceuticals Display Amyloid-like Properties upon Exposure to Conditions of Stress, Indicating Protein Misfolding — During manufacturing and storage, biopharmaceuticals may also become exposed to various conditions of stress that can potentially underlie protein misfolding and the formation of amyloid-like properties.
…….Our results point to a common mechanism by which the immune system perceives misfolded proteins. We hypothesize that this lies in the changed conformation of the protein backbone itself. This implies that the innate immune system may be activated by recognition of the amyloid-like properties of misfolded protein. …
Time to fight the new global pandemic of chronic diseases
New cases of chronic noncommunicable diseases (NCDs) such as heart disease, stroke, cancer, diabetes and chronic lung disease are exploding throughout the world, even in the poorest countries. These conditions account for 63 percent of deaths globally, and 80 percent of those deaths are occurring in low- and middle-income countries. Chronic diseases are also incredibly disabling and have a major negative impact on economic development, as they occur at a much earlier age and rob families of their breadwinners.
Chronic disease to cost $47 trillion by 2030: WEF
"This is not a health issue, this is an economic issue…"
Mental health, which is typically left off lists of leading NCDs, will account for $16 trillion -- a third of the overall $47 trillion anticipated costs.
What's killing us? Diseases that will kill 9 of 10 Americans
…..cancer, heart disease, diabetes, and a variety of other chronic ailments. And worse, unlike some infectious diseases, they're quite preventable.
This new, ultra-deadly pandemic threat is caused by we, ourselves. Sedentary lifestyles, poor eating habits, smoking, and other high-risk behavior causes most of these diseases. ….
More than anything, the root causes are apathy and sloth.
individually or collectively, is NOT going to change the reality that industry has made our world a place of sickness, not health.
Fact is, industrial activities, including food processing and drug manufacturing, create infectious misfolded proteins. In turn, infectious misfolded proteins cause numerous debilitating, degenerative and disabling diseases - referred to generically as chronic "noncommunicative diseases" (NCD's) - five of which are now pandemic. "Mental illness" is on the list.
But even though industrial activities like food processing and drug manufacturing are well-known to create infectious misfolded proteins, and cause disease, people are being blamed for "making themselves sick."