AIDS, Alzheimer's, Cancer - and Mad Cow Prions. What's the Story?

Cancer and virtually all the "modern diseases of civilization" - aka age-related and chronic diseases - are caused by infectious proteins called prions or "proteinaceous infectious particles." Prions use the immune system to spread in the body, relocating to cause a variety of diseases from Mad Cow to AIDS, Alzheimer's, diabetes 2, obesity, ALS and more. Prions are created in industrial processes, and spread around the world via product distribution systems for international trade - then they mutate and evolve to infect any cell they might touch, and go airborne too. The major stakeholders of corporate industry identified the 'problem' as early as World War I, but chose to play the crisis as a business opportunity, for profit, and to develop the situation as a population control strategy. Their master plan involved letting people get sick, building a lucrative drug and medical industry to treat the symptoms, controlling research to protect the contaminating industries - and profiting across the board. Any damning information that got out was suppressed or ridiculed to avoid accountability and legal liability. Instead, the financial elite positioned to justify mass quarantines and human depopulation. Part of the quarantine and depopulation phase involves fearmongering - by blaming the victims and demonizing the sick, homeless and jobless. All the evidence indicates the elite are almost ready to move on the quarantine and depopulation phase of their strategy.

The prion disease problem is real. The solution is not more drugs or new vaccines - nor will quarantining the already infected fix anything. But if we want to discuss more acceptable solutions, we do need to understand the "problem."

…And if we want to understand the "protein-folding problem" - and it's implications - we need to totally rethink our concepts of biology, disease and evolution. Not to mention the common industrial processes that create prions, the global distribution systems that disseminate them - and our planet's economic system.

If we want to be responsible, we have a huge task before us - nothing less than altering a bunch of dominant scientific and social memes and creating new, more accurate and constructive ones.

If we are not responsible in our discussions and coverage - we simply will accelerate the strategy for mass quarantines and depopulation.

We all need to think about re-educating ourselves, and sharing our information. For example….

Prions cause disease, yes, but they also can be "good guys." One of the oldest known prion diseases is sickle-cell disease - caused by conformation problems with the hemoglobin protein. …The same protein conformational "problem" that causes sickle-cell disease also protects carriers from debilitating malarial infections.

Sickle-cell disease, usually presenting in childhood, occurs more commonly in people (or their descendants) from parts of tropical and sub-tropical regions where malaria is or was common. One-third of all indigenous inhabitants of Sub-Saharan Africa carry the gene,[2] because in areas where malaria is common, there is a fitness benefit in carrying only a single sickle-cell gene (sickle cell trait). Those with only one of the two alleles of the sickle-cell disease, while not totally resistant, are more tolerant to the infection and thus show less severe symptoms when infected.

Much evidence indicates that ALL prions (and prion diseases) have the ability to confer benefits and positive evolutionary effects.

One of the top prion researchers is Susan Lindquist - a member of the Whitehead Institute, Professor of Biology at MIT and Investigator of the Howard Hughes Medical Institute. Lindquist has a handle on everything from the science to the social dangers.

Lindquist Lab

Work in our lab covers a broad range of topics unified by one theme: the protein-folding problem.

Through biochemistry and genetics we investigate the mechanisms of protein folding and the consequences of misfolding. Because protein-folding problems are universal, we move back and forth between simple and complex organisms (yeast, rodents, and human cells). We investigate how protein conformational changes provide epigenetic mechanisms of inheritance, sculpt phenotypic landscapes, shape evolutionary process, and cause devastating neurodegenerative diseases. We are also making progress in deciphering the enigmatic structures of prions and amyloids. One implication of our work is that the protein-folding problem isn’t always a problem. The very same types of misfoldings that cause dreadful diseases in some circumstances can have beneficial effects in others. The protein-folding problem is as ancient as life itself; it makes sense that evolution would occasionally, perhaps even often, use it to advantage.

For YouTube fans, a recent Susan Lindquist video from Yale:


And a streaming video from the Whitehead Institute featuring Lindquist:
streaming.wi.mit.edu...

For readers, some quick info, easy to scan:

Epigenetics in the Extreme: Prions and the Inheritance of Environmentally Acquired Traits

Prions are an unusual form of epigenetics: Their stable inheritance and complex phenotypes come about through protein folding rather than nucleic acid–associated changes. With intimate ties to protein homeostasis and a remarkable sensitivity to stress, prions are a robust mechanism that links environmental extremes with the acquisition and inheritance of new traits.

Prions, protein homeostasis, and phenotypic diversity

Prions are fascinating but often misunderstood protein aggregation phenomena. The traditional association of the mammalian prion protein with disease has over- shadowed a potentially more interesting attribute of prions: their ability to create protein-based molecular memories. In fungi, prions alter the relationship between genotype and phenotype in a heritable way that diver- sifies clonal populations. Recent findings in yeast indicate that prions might be much more common than previously realized. Moreover, prion-driven phenotypic diversity increases under stress, and can be amplified by the dynamic maturation of prion-initiating states. In this report, we suggest that these qualities allow prions to act as ‘bet-hedging’ devices that facilitate the adaptation of yeasts to stressful environments, and might speed the evolution of new traits.

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More reading:

Protein Homeostasis and the Phenotypic Manifestation of Genetic Diversity: Principles and Mechanisms

Abstract
Changing a single nucleotide in a genome can have profound consequences under some conditions, but the same change can have no con- sequences under others. Indeed, organisms can be surprisingly robust to environmental and genetic perturbations. Yet, the mechanisms un- derlying such robustness are controversial. Moreover, how they might affect evolutionary change remains enigmatic. Here, we review the recently appreciated central role of protein homeostasis in buffering and potentiating genetic variation and discuss how these processes mediate the critical influence of the environment on the relationship between genotype and phenotype. Deciphering how robustness emerges from biological organization and the mechanisms by which it is overcome in changing environments will lead to a more complete understanding of both fundamental evolutionary processes and diverse human diseases.

SUMMARY LIST
….6. Environmental stress is a major contributor to genetic and phenotypic variation in two fundamental ways. First, it can increase the amount of genetic variation available for selection by increasing the rate of sexual reproduction, recombination, and mutation. Second, environmental stress can also affect the phenotypic expression of genetic variation because it is intimately linked to protein homeostasis.
7. In yeast, prions are emerging as an important bet-hedging mechanism for the inheritance of new phenotypes, based on stress-induced changes in cellular proteostasis, that lead to heritable, self-perpetuating changes in protein folding and function.

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Here's an incomplete list of "protein misfolding diseases."



Here's another, with some duplicates, other new ones.

Any thoughts on this bit, anyone?

The master plan involves letting people get sick, building a lucrative drug and medical industry to treat the symptoms, controlling research to protect the contaminating industries - and profiting across the board. ...The financial elite positioned to justify mass quarantines and human depopulation. Part of the quarantine and depopulation phase involves fearmongering - by blaming the victims and demonizing the sick, homeless and jobless. All the evidence indicates the elite are almost ready to move on the quarantine and depopulation phase of their strategy.


~ sofi

I don't want to dig in too deep and risk T&C, but there have been discoveries mentioned in alternative reports (other than MSM-approved and sanctioned) that suggest some alternative substances have been effective against some of the diseases mentioned in your prion thread. I suggest Big Pharma may already know some of these are beneficial and it would cut into their goldmine dreams.

I agree there appears to be a new Pharma conspiracy in the works with prion research and treatment. Look closely at that list of prion-related diseases and think back to some threads in the closed Alt. Subs. forum and ask yourself if there may be a connection.

I think of the ancient spice trade that opened up the Greco-Roman and Roman-India trade routes that controlled the world economy in the Middle-Ages. What is driving the world economy from behind in modern times? Medicines. We cannot allow corporate interests to control those for their gain, our health detriment, and basically control over our lives and deaths. Medicines are largely herbal and plant extracts synthesized in labs - spices.

Sasha Shulgin and Augustus Owsley Stanley III were some of my modern-day heros. These men were the type that could make a big difference for our future.

Incredible Sofi, is just so much to learn about why modern days are full of new diseases and no cure for them but treatments.

We blame it on anything from diet, to environment to genetics, while I agree with the first two the third one makes no sense when our ancestors were more resilient fighting diseases.

As long as our medical system is hijacked by big interest we are nothing but their milking cows and Guinea pigs.

A very intelligent informative thread. Thinking outside of the Matrix's box.

After reviewing the thread I dare ask the question?

Why have done nothing?, because we traded in our Freedoms, Health, Education, Sustinance and Energy for Security and Pleasure.

The Price is that AIDS, Lime Disease (Created in Montauk Island) , Bird Flu, N1H1... the list goes on, are all created for a specific purpose, to push the limitations of our bodies, to kill us of if necessary, but more importantly to create profit for Big Pharma and excuse for them to exsist.

Thank you for the Thread as well, I enjoyed the read and video.

The master plan involves letting people get sick, building a lucrative drug and medical industry to treat the symptoms, controlling research to protect the contaminating industries - and profiting across the board.

This is Big Pharma and this is how the money rolls in. The disease and the cure separately are far less valuable then the disease and cure together. Frightening thought that there are only 3 pharmacological companies in the world controlling the entire system.

...The financial elite positioned to justify mass quarantines and human depopulation. Part of the quarantine and depopulation phase involves fearmongering - by blaming the victims and demonizing the sick, homeless and jobless. All the evidence indicates the elite are almost ready to move on the quarantine and depopulation phase of their strategy.

I'm not so sure about this part of the plan. I would agree that demonizing (or blame shifting) to the sick, homeless and jobless is a well practiced smokescreen, its function meant to distract (a slight of hand at a magic show) to keep the general public looking at everything but them, but I do not buy the idea of a depopulation "master plan" it would actually defeat the purpose of Big Pharma. They are in the business of disease (creating and destroying) but the bottom line: profit margin.

reply to post by soficrow


Interesting theory.

Personally, I see all of the food additives, preservatives, and hormones being responsible.

These corporations pay out the nose for research and then pay off the F.D.A. to allow it.

Certain amounts of bad things are allowed in because they do no permanent harm.

The problem is that there is far more harm in allowing any type of harm.

Ben and Jerry's boycotts using any milk where the cows are pumped full of RBGH.

Just one example where people with ethics, morals, and beliefs stand their ground.

reply to post by LadySkadi


PLEASE NOTE: I make reference to political figures here, and it may seem like I'm favoring political parties - but I am NOT - I think a) our governments are run by corporations, and b) no party or individual at any level has the power to stand up against the Global Corporate Ruling Class.

...The financial elite positioned to justify mass quarantines and human depopulation. Part of the quarantine and depopulation phase involves fearmongering - by blaming the victims and demonizing the sick, homeless and jobless. All the evidence indicates the elite are almost ready to move on the quarantine and depopulation phase of their strategy.

I'm not so sure about this part of the plan. I would agree that demonizing (or blame shifting) to the sick, homeless and jobless is a well practiced smokescreen, its function meant to distract (a slight of hand at a magic show) to keep the general public looking at everything but them,

Certainly it's a smokescreen, but it's much more than that too. We're being set up. No question.

There is NO doubt industrial contamination, pollution and common products create prions - and infectious prion-related chronic diseases - which are now pandemic. But the push is on big-time to blame the victims for the prion-related Chronic Disease Pandemic. This is just one sample of the vitriol in the MSM:

What's killing us? Diseases that will kill 9 of 10 Americans …cancer, heart disease, diabetes, and a variety of other chronic ailments. And worse, unlike some infectious diseases, they're quite preventable.

This new, ultra-deadly pandemic threat is caused by we, ourselves. Sedentary lifestyles, poor eating habits, smoking, and other high-risk behavior causes most of these diseases. In a time when humans know so much about their own biology and virtually everyone should be living to old age, millions are dying relatively young because they cannot manage their health.

More than anything, the root causes are apathy and sloth.

…Sounds a lot like the rhetoric that justified the Eugenics policies of the early 1900's - and the imprisonments and sterilizations, not to mention Hitler's camps. ….Eugenics policies are definitely back, but now they're camouflaged, called "genetic" or "age-related." Just check your insurance policy - you're not covered for anything real - according to the underwriters, everything that makes you sick is genetic or "lifestyle related," or maybe a "natural" consequence of aging. It's been going for a while. All that's changed is now the global corporate government is arm wrestling with nations for full control over public policy.

...I do not buy the idea of a depopulation "master plan" it would actually defeat the purpose of Big Pharma. They are in the business of disease (creating and destroying) but the bottom line: profit margin.

You're right - the bottom line IS profit. And the Chronic Disease Pandemic is cutting profits in a major way. According to the World Economic Forum (WEF), the Chronic Disease Pandemic will cost $47 trillion by 2030 - and it's already bankrupting many nations. Moreover, "NCDs "have the potential to not only bankrupt health systems but to also put a brake on the global economy."" The icing on the profit cake is that all Big Pharma's blockbusters are going off-patent - they are about to lose their profits, pretty much overnight. And they have NO new blockbusters in the pike. ….So what do you think? Is that accidental oversight or long-term strategy?

In short, I think larger financial interests will be served, and far bigger profits made, if the Corporate Ruling Class puts Big Pharma on the back burner for a while.

Remember, most chronic diseases result from protein conformation "problems" - they're prion-related. But all the studies and agencies refer to them discreetly and euphemistically as "non-communicable diseases" (NCD's).
NOTE: They're saying non-communicable, not non-infectious.

…Also note the unprecedented inclusion of mental health costs in the tally: "Mental health, which is typically left off lists of leading NCDs, will account for $16 trillion -- a third of the overall $47 trillion anticipated costs."




........continued......

Chronic disease to cost $47 trillion by 2030: WEF

The global economic impact of the five leading chronic diseases -- cancer, diabetes, mental illness, heart disease, and respiratory disease -- could reach $47 trillion over the next 20 years, according to a study by the World Economic Forum (WEF).

…"This is not a health issue, this is an economic issue -- it touches on all sectors of society,"….

Mental health, which is typically left off lists of leading NCDs, will account for $16 trillion -- a third of the overall $47 trillion anticipated costs. ….

… these numbers suggest NCDs "have the potential to not only bankrupt health systems but to also put a brake on the global economy," he added.

In summary, the Chronic Disease Pandemic is being framed as an economic issue, not a health priority - and the solutions will be economic, not medical.

Big Pharma is not separate and distinct from the rest of the ruling financial system - it's just one arm - a "product line."

Study shows powerful corporations really do control the world's finances

Who Runs the World ? – Network Analysis Reveals ‘Super Entity’ of Global Corporate Control

Meet the Global Financial Elites Controlling $46 Trillion In Wealth

Clearly, Big Pharma is profitable, yes, but it's just one holding, and replaceable.

The Corporate Ruling Class switches gears, and changes directions and frontline products all the time. And it looks like that's the plan here.

Remember - all Big Pharma's blockbusters are going off-patent - they are about to lose their profits, pretty much overnight.

big-profit blockbusters are about to go off patent. Between now and 2015, $250 billion in drug sales are about to disappear into the generics market.

The 10 Biggest-Selling Drugs That Are About to Lose Their Patent

The imminent arrival of the dreaded "patent cliff" has been haunting the pharmaceutical industry for years, and it's finally here. With patents on many blockbuster drugs about to expire, an estimated $250 billion in sales are at risk between now and 2015…

So they're losing $250 Billion in drug sales - AND facing $47 Trillion in liability costs for the Chronic Disease Pandemic. You do the math.

Believe me, they know exactly what they want - and how to convince the general population to climb on board and get with the program.

The Global Corporate Government's goal is to keep the population working but dependent on treatment, and get rid of the "useless eaters" as soon as they succumb or become too costly to keep going.

...Current "drug shortages" are a power play - part of a strategy to implement full-bore Eugenics Policies. Also see wiki Eugenics.

...American corporate philanthropies launched a national campaign of ethnic cleansing in the United States, helped found and fund the Nazi eugenics of Hitler, and then created the modern movement known as “human genetics.”

….Please, tell me what you think. Is it accidental, that $250 Billion loss from drugs going off-patent? And the complete lack of new blockbuster patents, that's accidental too? Just a couple little fiscal oversights? Or could those coincidences indicate a long-term strategy? Maybe suggest a complete change of direction is in the works? Perhaps a big change in investment priorities?

reply to post by SpartanKingLeonidas

Interesting theory.

Personally, I see all of the food additives, preservatives, and hormones being responsible.

Our "theories" don't negate one another. Prions are the mechanism; additives, preservatives and hormones are "initiating triggers" that can cause proteins to misfold, misassemble or misprocess. When that happens, infectious prions are created, and spread through the body, causing disease.

...Different exposures affect different proteins, and create different prions. Also, if the exposure is low level and transient, our bodies flush the prions; if the exposures are high level or constant, the prions tend to stick around and propagate. It's an evolutionary process - evolution in action, really - a way to adapt to changing environments and develop new traits.

...The traditional association of the mammalian prion protein with disease has over-shadowed a potentially more interesting attribute of prions: their ability to create protein-based molecular memories. ...prion-driven phenotypic diversity increases under stress, and can be amplified by the dynamic maturation of prion-initiating states. ...these qualities allow prions to act as ‘bet-hedging’ devices that facilitate ...adaptation ...to stressful environments, and might speed the evolution of new traits.

[web.wi.mit.edu...]Scroll down to link[/url]

Certain amounts of bad things are allowed in because they do no permanent harm.

But they DO cause permanent harm: they create prions. And prions and the diseases they cause are not just transmissible, they're inheritable.

The problem is that there is far more harm in allowing any type of harm.

Oh yeah.

Ben and Jerry's boycotts using any milk where the cows are pumped full of RBGH.

Just one example where people with ethics, morals, and beliefs stand their ground.

Past time for everyone to get informed and stand their ground. imho.

Sofi, this information is so useful, very interesting, I am trying to absorve everything, specially when I know that in my case I am so sensitive to prescribed medications, I am now working with an acupuncturist and herbalist to treat some of the side effects that I got from the medications I received after my gallbladder surgery.

I always tell my husband that if I happen to get a chronic disease that required strong medical drugs it will kill me.

So I am trying to get into natural medicine for prevention.

We need to reform our government, get them off the private interest payroll and forced them to give people choices of how they want to used medicine.

Is outrageous what we have been forced into in this country for profits.

reply to post by soficrow


Not even through the OP but wanted to comment that one of the deepest problems and challenges of BSE, prion contaminants are that they can be 'masked' through artificial and chemical means, at least long enough for the infection to reach the public and possibly change the very structure of the DNA.

This bombardement strategy is so efficient that it throws everyone outside the plan into a form of zombisim type denial. Everyone.

Unless you are a complete nutjob and fully under the wire you just cannot avoid it, as you stated it has become an infection which travels through water, soil errosion, rain cycles and wind even if you never directly consume or inhale the toxins.

There must be ways to combat this, simple suppliments which can flush this out of ones body. How do some people develop the sickness and others never show any signs?

Also are certain people such as the all too curious past President Reagan given this purposefully? How many more will be subject to contamination to silence them?

If you look at the statistics which were available only a few short years ago relating to Alzheimers verses today, it is utterly frustrating because so much of that info is no longer to be discovered. So many 'facts' relating to this mega industry has been rewritten from what I have seen.

Perhaps what you provide in the OP has truth and this did begin back during the early 19th century, but it is possible that BSE/prion disease has worked better than they could have ever planned by its own mutations and availability. One thing for sure is that it is happening faster than any of them could have hoped for.

I read several years ago that there was only 5 thousand people in the US reported to have Alzheimers, and within 5 years that number jumped to over 5 million! Now some said it was because of under reporting, but I never bought that lie.

Speaking of President Reagan, he developed the disease so much faster than the people I have experienced with the same diagnosis...

A couple years ago I experiemented on my now dead great Aunt, who was quite the interesting person and who I believe could have been also intentionally contaminated to keep her silent, anyway, I saw her almost go back to normal for a short while by using Vit. D50 and a couple other vitamins. I can explain more about that if asked.

My point is that with all the specialized care, why do some people in higher circles also die of certain prion related illness's and far faster than the average person?

Now lets hope that some of the missing viruses do not become recombination nightmare scenarios...

Back to finish reading your thread, but yeah, this subject is insane...

reply to post by soficrow


The socioeconomic implications are the most rediculous theatrics being played as well. Deny the health benifits of eating Vegan diets and then push for more industrialized farming techniques rather than local and organic methods.

The over use of antibiotics and the truth behind not allowing animals to be tested is telling as well.

Just bumping this back up.

Soficrow, do you think that this is being played out in the timeline they expected? Also how did they plan to escape the effects as well once it became so widespread?

reply to post by antar

this subject is insane...

The ONLY way I am able to study prions without despairing, is to recognize them as a mechanism for adaptation and evolution - maybe the primary mechanism.

....We have changed our world - quite radically, as it turns out. Even the molecules in our world are affected - so the molecules change too, in order to survive. Molecules adapt and evolve, just like real lifeforms. ...Proteins are molecules; prions are proteins that are changing, adapting and evolving. And it turns out that adapted molecules like prion proteins help real lifeforms adapt and evolve in turn. It's quite simple really. A no-brainer when you think about it. We should have expected it.

reply to post by antar


Sorry - missed this one.

Soficrow, do you think that this is being played out in the timeline they expected?

Pretty close. ...They've been aware, strategizing, positioning and preparing for a long time. The telling events were the major looting and pillaging between 2001-2008, and of course the so-called global financial crisis when they pulled all the cash. They're ready to move. Just need to clear out the riffraff.

Also how did they plan to escape the effects as well once it became so widespread?

TPTB are viewing prions as "disease agents" - and not evolutionary mechanisms, which they clearly are. ...The focus is on (social and geographic) isolation, intervention, stem cell banks, interpheron and the like. I think the really rich stopped getting organ transplants because the diseases are so widespread - only the very rich are buying organs these days because they can't afford the "good" stuff..

The problem is, medical interventions seek to restore the body, to put it back the way it was - which neutralizes the adaptive effects, and denies the need for adaptation and evolution. Big mistake.

The rest of us really are way better off. We need to go with the evolutionary flow - it's the best thing to do by far.

Not to say we can't try and make ourselves feel better, and slow down the disease processes. The best prion therapeutics are still natural - green tea; curcumin from curry, cumin or turmeric; sage; and (unnatural) antihistamines and statins. Go with anti-inflammatories whenever you can - like cinnamon, aspirin - inflammation seems to trigger or support prion propagation.

New Inhibitors of Scrapie-Associated Prion Protein Formation in a Library of 2,000 Drugs and Natural Products

Several classes of compounds were represented in the 17 most potent inhibitors, including naturally occurring polyphenols (e.g., tannic acid and tea extracts), phenothiazines, antihistamines, statins, and antimalarial compounds. ...many are either approved human drugs or edible natural products...

reply to post by marg6043

Sofi, this information is so useful, very interesting, I am trying to absorve everything, specially when I know that in my case I am so sensitive to prescribed medications, I am now working with an acupuncturist and herbalist ...

Good. ...I do take meds, but I'm very cautious - try to find the balance, and take only the best of what East, West and otherwise has to offer.

I always tell my husband that if I happen to get a chronic disease that required strong medical drugs it will kill me.

We really need personalized medicine - sometimes the meds that work on one person kill the next patient. Really. ...That's because they treat the disease, not the person. Wrong.

So I am trying to get into natural medicine for prevention.

It's true - and ounce of prevention really is worth a pound of cure.

We need to reform our government, get them off the private interest payroll and forced them to give people choices of how they want to used medicine.

Is outrageous what we have been forced into in this country for profits.

Yes. That's what got us into this mess in the first place - and it sure will NOT get us out.