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This is the first report of an EHEC virulence plasmid containing a complex antibiotic resistance locus, and raises the concern that antibiotic use will coselect for virulence determinants, leading to increased disease potential in both commensal and pathogenic E. coli populations.
This does not happen in the wild where you have a strain that is resistant,” he says. “This looks like, genetically, that it had to be engineered.