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More and more pathogens are becoming immune to antibiotics. Some bacteria can no longer be combated. The World Health Organization WHO is warning about resistance to drugs which were once so potent. The WHO’s director-general Margaret Chan has pointed out that if measures are not taken quickly, it may soon not be possible to treat many frequently occurring infections. Figures released by the WHO show that in 2010 nearly half-a-million people were infected with a strain of tuberculosis which is resistant to many antibiotics – one third of those infected died. The Organization states that the growing spread of resistant pathogens is attributable to the indiscriminate use of penicillin and other antibiotics.
“We have already identified 20 of these short chains of amino acids which kill numerous microbes, including enterococci, yeasts and molds, as well as human pathogenic bacteria such as Streptococcus mutans, which is found in the human oral cavity and causes tooth decay. Even the multi-resistant hospital bug Staphylococcus aureus is not immune, and in our tests its growth was considerably inhibited,”
As the new peptides contain cationic amino acid residues, they can bond with the negatively charged bacterial membrane and penetrate it.
“Antibiotic peptides unlock their microbicidal effect within a few minutes. They also work at a concentration of less than 1 µM, compared with conventional antibiotics which require a concentration of 10 µM,”
“This is a definite possibility because the short-chain peptides tested during the project do not exhibit any allergological risk on being added to foodstuffs,”
In Russia, mixed phage preparations may have a therapeutic efficacy of 50%. This equates to the complete cure of 50 of 100 patients with terminal antibiotic-resistant infection. The rate of only 50% is likely to be due to individual choices in admixtures and ineffective diagnosis of the causative agent of infection.
That's the good news or the "updside".
Originally posted by Griffo
The best parts of this, is that these peptides can target viruses as well as bacteria and fungi. They also do not harm human body cells. The food sector could also greatly benefit from these peptides, improving the shelf-life of food.
I can't tell you how annoying it is to me to not only see my friends with a cold or a flu ask the doctor for an antibiotic, but that's only superseded by the shock and horror I feel when the doctor succumbs to the "pressure" to "prescribe an antibiotic" to fight what is clearly a viral infection. Am I the only one who's shocked by this?
1. Talk with your healthcare provider about antibiotic resistance:
* Ask whether an antibiotic is likely to be beneficial for your illness
* Ask what else you can do to feel better sooner
2. Do not take an antibiotic for a viral infection like a cold or the flu....
6. If your healthcare provider determines that you do not have a bacterial infection, ask about ways to help relieve your symptoms. Do not pressure your provider to prescribe an antibiotic.
So to summarize, there's NO BENEFIT to using these antibacterial products. So why use them on just that basis alone? In the meantime, "More studies examining resistance issues related to these products are needed." meaning we can't say definitively that they do or don't contribute to the resistant bacteria problem in humans, though they have been shown to contribute to resistant bacteria in the laboratory. [/rant]
Q: Are antibacterial-containing products (soaps, household cleaners, etc.) better for preventing the spread of infection? Does their use add to the problem of resistance?
A: An essential part of preventing the spread of infection in the community and at home is proper hygiene. This includes hand-washing and cleaning shared items and surfaces. Antibacterial-containing products have not been proven to prevent the spread of infection better than products that do not contain antibacterial chemicals. Although a link between antibacterial chemicals used in personal cleaning products and bacterial resistance has been shown in vitro studies (in a controlled environment), no human health consequence has been demonstrated. More studies examining resistance issues related to these products are needed.
The Food and Drug Administration (FDA) Nonprescription Drugs Advisory Committee voted unanimously on October 20, 2005 that there was a lack of evidence supporting the benefit of consumer products including handwashes, bodywashes, etc., containing antibacterial additives over similar products not containing antibacterial additives.
Originally posted by dizzylizzy
Phage was widely used in the Soviet Union as an alternative to accepted anti-biotics.
Of course the pharmaceutical industry will do its upmost to stop any more research.
Here is a vid from the BBC
Phage the virus that cures
Sorry I ignored the OP., I just get so angry about the drug industry.
"Antibiotic resistant infections" happen as a result of taking too much antibiotics in the past.
Do you really think that they will allow it?
Do you know how much money pharmaceutical industry makes of antibiotics every year?
Not just that but as it is mentioned in that article antibiotic peptides also destroy viruses. Imagine curing AIDS, do you seriously think that will happen?