reply to post by jrmcleod
Myth: The American Diabetes Association knows what they're talking about!
Fact: They certainly do not! (nice try though, Jr)
Sugar is quite the ambiguous term, firstly, and may refer to many types of sugars, many of which aren't inherently dangerous to the metabolic system.
Let's assume, however, that when you, and the ADA, refer to sugar, you're talking about table sucrose (fructose/glucose) or HFCS
Fact: Biochemistry has precedence over any 3 letter word association, such as ADA.
Biochemistry Summary: Fructose consumed frequently, whether in the form of sucrose or HFCS, will undoubtedly lead to hepatic insulin resistance
(that's the liver, fyi), which leads to increased hyperinsulinemia, which leads to hyperglycemia...which, btw, is Type 2 DIABETES.
Biochemistry Detail: Fructose is metabolized ONLY in the liver, the byproduct of which is VLDL (triglycerides). An overload of fructose will lead to
hypertriglyceridemia, which is essentially elevated serum VLDL(very low density lipoprotein), which has an unpleasant "side-effect" of becoming LDL.
Regardless, this chronic state of elevated blood lipids leads to, at least the science suggests, insulin resistance in the liver (hepatic insulin
Hepatic IR, in very basic terms, means the insulin receptors in the liver aren't very...receptive, they become less sensitive to insulin uptake.
Since insulin plays a vital role in metabolic function in the liver, the pancreas produces more insulin to compensate, thus leading to chronically
elevated blood levels of insulin. This situation is what ultimately leads to systemic insulin resistance (whole-body) going from the muscles, then
eventually arriving at a halt when the fat cells become insulin resistant, which is the point at which Type 2 diabetics become insulin dependent
(their bodies are unable to produce enough insulin to clear blood glucose to the cells because the cells are resistant).
So, yes, sugar does cause diabetes through insulin resistance. It doesn't cause Type1 diabetes, that'd be pretty absurd. It does, however, cause
type 2 diabetes that can lead to type 1, or insulin dependency.