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Originally posted by cybertroy
Look, my friend, I already know antioxidants work, as well do plenty of people. There isn't much debate to be had from the people who know and have seen that antioxidants work.
The goal of the collaboration is to help people make well informed decisions about health care by preparing, maintaining and ensuring the accessibility of systematic reviews of the effects of health care interventions. The principles of the Cochrane Collaboration are:
building on the enthusiasm of individuals
keeping up to date
striving for relevance
enabling wide participation
We found no evidence to support antioxidant supplements for primary or secondary prevention. Vitamin A, beta-carotene, and vitamin E may increase mortality. Future randomised trials could evaluate the potential effects of vitamin C and selenium for primary and secondary prevention. Such trials should be closely monitored for potential harmful effects. Antioxidant supplements need to be considered medicinal products and should undergo sufficient evaluation before marketing.
Plain language summary
No evidence to support antioxidant supplements to prevent mortality in healthy people or patients with various diseases
Previous research on animal and physiological models suggest that antioxidant supplements have beneficial effects that may prolong life. Some observational studies also suggest that antioxidant supplements may prolong life, whereas other observational studies demonstrate neutral or harmful effects. Randomised trials have largely been neutral. We need evidence from randomised trials to decide if antioxidant supplements should be used for prevention.