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Volcanic eruptions, giant squid and sea lice have all been invoked to explain the wild swings in British Columbia's famed Fraser River sockeye-salmon runs.
Now scientists are raising the possibility that a mysterious virus is responsible for killing huge numbers of Pacific salmon before they reach their spawning grounds.
Possibly associated with leukemia, lymphoma...
Some observers speculate the virus may be linked to fish farms, but others say it could be a natural, but until now unrecognized, threat to Pacific salmon.