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A remarkable study published in the Cochrane Library found no evidence of benefit for influenza vaccinations and also noted that the vast majority of trials were inadequate.
The study, "Vaccines for preventing influenza in healthy adults", is damning of the entire pharmaceutical industry and its minions, the drug testing industry and the medical system that relies on them.
WARNING: This review includes 15 out of 36 trials funded by industry (four had no funding declaration). An earlier systematic review of 274 influenza vaccine studies published up to 2007 found industry funded studies were published in more prestigious journals and cited more than other studies independently from methodological quality and size. Studies funded from public sources were significantly less likely to report conclusions favorable to the vaccines. The review showed that reliable evidence on influenza vaccines is thin but there is evidence of widespread manipulation of conclusions and spurious notoriety of the studies. The content and conclusions of this review should be interpreted in light of this finding..
From RCTs, live vaccines showed an efficacy of 79% (95% confidence interval (CI) 48% to 92%) and an effectiveness of 33% (95% CI 28% to 38%) in children older than two years compared with placebo or no intervention. Inactivated vaccines had a lower efficacy of 59% (95% CI 41% to 71%) than live vaccines but similar effectiveness: 36% (95% CI 24% to 46%).
Influenza vaccines are efficacious in children older than two years but little evidence is available for children under two.
In children under two, the efficacy of inactivated vaccine was similar to placebo.
It was surprising to find only one study of inactivated vaccine in children under two years, given recent recommendations to vaccinate healthy children from six months old in the USA and Canada. If immunisation in children is to be recommended as public-health policy, large-scale studies assessing important outcomes and directly comparing vaccine types are urgently required.
Influenza vaccines have a modest effect in reducing influenza symptoms and working days lost.
Study Verifies That There Is No Value In Any Flu Vaccine
Originally posted by Klassified
It would be interesting to know if anyone else has had problems with the flu vaccine.
And also those who have had no problems at all.