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Originally posted by kimish
reply to post by VneZonyDostupa
Actually Tylenol is not an non-steroidal anti-inflammatory. But it should not cause pain however.
www.tylenol.com.../arth/subfalert.incedit on 8-11-2010 by kimish because: (no reason given)
Acetaminophen Toxicity
Acetaminophen should be respected as a drug with severe toxicities. Liver failure from acetaminophen overdose is the most serious side effect and can vary from mild to severe. The extreme case is seen in acute liver failure, which includes coagulopathy and encephalopathy. In one study 27% of these patients died without liver transplantation. In healthy adults, a dose of 4 g daily can cause alanine aminotransferase (ALT) elevations within 1 week.
Acetaminophen was also shown to increase the risk of major cardiovascular events (nonfatal myocardial infarction, fatal congestive heart failure, nonfatal and fatal stroke) with an increased risk of 1.68. Therapeutic doses (2-4 g/day) of acetaminophen are associated with increased risk of serious upper gastrointestinal events. Acetaminophen is also associated with hypersensitivity reactions, serious hematologic disorders, and skin disorders ranging from rashes to toxic epidermal necrolysis.