posted on Sep, 8 2010 @ 12:53 AM
reply to post by TiredofControlFreaks
Smoking causes irritation and damage to the lining of the airway. As damage continues, goblet cells increase in size and number to coat the cells
that line the airway with more mucus. When the production of mucus isn't enough to keep up with the damage....we end up with cell injury. They stop
functioning properly and die. They're then replaced by new cells which end up going through the same cycle. Eventually, the damaging effects cause
a malignant transformation in ONE cell will not die, and tumor growth ensues.
I'm sorry....I haven't studied the history or the studies involved with this RARE, and do understand it's rare, disease. The epidemiological
evidence seems to point towards a combination of cigarette smoking AND drinking. Both independently
show a negligible effect on tumor growth.
But, most of the studies ARE observational, implying that there is no real arrow of causation. The lab studies of cancer would suggest that smoking
does indeed have a direct, independent association with esophageal cancer incidence.
Edit to add: If you're arguing that commercialized cigarette smoke is safe and doesn't cause cancer...you should probably stop posting.
[edit on 8-9-2010 by DevolutionEvolvd]