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(Aug. 21) -- New research shows that major earthquakes have struck southern California far more frequently than previously thought -- and the next one could be just around the corner. The study from geologists at the University of California Irvine and Arizona State University showed that massive quakes -- of magnitude 6.5 or greater -- have hit the region's San Andreas fault line at intervals of between 45 and 144 years. With the last major earthquake in 1857, that means Southern California is overdue a massive quake.