I'm upping this thread, very sensitive subject.
The University of Arkansas abstract is here
Modeling Biopotential Signals and Current Densities of Multiple Breast Cancerous
Cells
The fulltext is made free by the 1st author.
emag.eleg.uark.edu/published/ahm4.pdf
This paper appears in: Biomedical Engineering, IEEE Transactions on
Issue Date: Sept. 2010
Volume: 57 Issue:9
On page(s): 2099 - 2106
ISSN: 0018-9294
Digital Object Identifier: 10.1109/TBME.2010.2049575
Date of Publication: 10 May 2010
Date of Current Version: 16 August 2010
Sponsored by: IEEE Engineering in Medicine and Biology Society
Abstract
This study presents a model to simulate the electrophysiological activities of multiple Michigan Cancer Foundation-7 (MCF-7) cells, the most studied
breast cancer cell line. The intercellular spacing of MCF-7 cells is estimated using the effective diffusion coefficient. Nonuniform finite-difference
discretization is implemented to accommodate for the contrast in size between the intercellular spacing and the cell dimension. The model computes the
amplitude and the spatiotemporal patterns of biopotentials and electric current densities at different cell division stages. The results show that the
biopotentials increase proportionally to the number of cells, especially when all cells are in the hyperpolarization stage. Also, the results show
significant electric current density in the intercellular gap between the cells.
[edit on 27-8-2010 by jjjtir]