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Scientists earlier found that mice missing one of a group of core developmental
genes known as the Hox genes developed an odd and rather unexpected pathology: the mutant animals groomed themselves compulsively to the point that they were removing their own hair and leaving self-inflicted open sores on their skin. Now, they've found a surprising connection between the Hoxb8 gene and the behavior that looks an awful lot like that of people with an obsessive compulsive spectrum disorder (OCD).
Capecchi now thinks based on the new findings connecting microglia to OCD-like behaviors in mice that the immune cells might not only monitor neural behavior but also modulate it, making sure it doesn't get out of hand. If they can't do their job properly, as in the Hoxb8 mutants, pathologies like the one they've seen in the mice may result.
Capecchi notes that disorders such as depression, autism, Alzheimer's, and OCD do tend to be associated with immune deficiencies. But it wasn't really clear which came first. Genome-wide association studies in schizophrenia and OCD had also turned up genes involved in the immune system. But again, the connection wasn't entirely clear.
Originally posted by xxcalbier
well even if this works on humans I just dont see how you could treat 3.5 billion woman for compulsive bathroom time.
Or 3.5 billion woman for the compulsive being an hour late for anything syndrome.
O the once a month every month from the age of 12 till death do you part syndrome . My god did they study how offton they can do this it would probly be many trips per woman to get them cured of everything.