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The results of the study by the research team led by China Medical University professor Chang Chawn-shang were published May 19 as the latest cover story in the U.S. journal Science Translational Medicine.
Taiwan’s National Science Council also held a news conference May 20 to introduce the study results, which have garnered a lot of international attention.
Chang noted epidemiology statistics showed that more male hepatitis B patients than their female counterparts develop liver cancer, but that the reasons had been unclear. He said his team was the first in the world attempting to use animal testing to prove that the androgen receptor regulates DNA reproduction and is the key mechanism prompting hepatocarcinogenesis, thereby revealing the reason why male hepatitis B patients develop liver cancer.