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Senenmut and Neferure
It is clear from the statues found of Senenmut, that he enjoyed a very close relationship with Neferure - the daughter of Hatshepsut (it is possible that this is the only sort of relationship he had with the King Hatshepsut, as teacher to her daughter. Although the converse may be argued - that Senenmut educated Neferure because of his relationship with Hatshepsut).