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Has DNA from PCV1 been found in other lots of Rotarix?
In its follow-up assessments, GlaxoSmithKline detected the presence of DNA from PCV1 in the working cell bank and viral “seed” used to produce Rotarix, confirming that the material has been present since the early stages of product development, including during clinical studies.
The GACVS viewed that the Rotarix vaccine's benefits far outweighed any known risk, and SAGE recommended that its use continue. "Given the absence of any known risk, SAGE strongly recommends the continued use of Rotarix for immunization programs, in particular in those parts of the world with under-5 mortality associated with rotaviruses," the group wrote.