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"This study provides a new opportunity to identify how androgens control sperm production, which could provide new insight for the development of new treatments for male infertility and perhaps new male contraceptives," said Michelle Welsh, Ph.D., co-author of the study, from the Centre for Reproductive Biology at The Queen's Medical Research Institute in Edinburgh, UK.
To make this discovery, Welsh and colleagues performed studies in two groups of mice. The first group of mice was normal, but the second group of mice was missing a gene from the peritubular myoid cells in the testis. This gene that was missing codes for the androgen hormone receptor, and when missing, sperm production was significantly decreased when compared to the normal group. The result was infertility.
"Although 'the pill' arguably has been liberating for women since its development in the 1960s, a similar birth control drug for men has been elusive," said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. "Not only does this research pinpoint androgenic hormones and their cellular receptors as prime targets for the development of new birth control drugs, but it promises to speed the development of new agents to boost sperm production."
More information: Michelle Welsh, Philippa T. K. Saunders, Nina Atanassova, Richard M. Sharpe, and Lee B. Smith Androgen action via testicular peritubular myoid cells is essential for male fertility. FASEB J. 2009 23: 4218-4230. doi:10.1096/fj.09-138347
Source: Federation of American Societies for Experimental Biology
Originally posted by buddhasystem
I can't wait for this pill to be commercially accessible. I am a father of multiple kids, I am macho and fertile as a thousand of horny demons.
Stop denigrating valuable research.
Originally posted by buddhasystem
I can't wait for this pill to be commercially accessible. I am a father of multiple kids, I am macho and fertile as a thousand of horny demons.
Stop denigrating valuable research.
Originally posted by buddhasystem
I can't wait for this pill to be commercially accessible. I am a father of multiple kids, I am macho and fertile as a thousand of horny demons.
Stop denigrating valuable research.
Originally posted by Kailassa
Is "macho" a euphemism for not being able to keep one's fly done up?
Originally posted by buddhasystem
I can't wait for this pill to be commercially accessible. I am a father of multiple kids, I am macho and fertile as a thousand of horny demons.
Stop denigrating valuable research.
Originally posted by buddhasystem
Originally posted by Kailassa
Is "macho" a euphemism for not being able to keep one's fly done up?
My fly is fine. I also have experience in search and rescue missions, where you have to revive frost-bitten people and in certain cases pack them up in body bags. If you have advice as to how to handle death of close friends that you witness, I'm all ears.
Originally posted by jdl79
reply to post by patmac
The book you are looking for is Ecoscience co-authored by John Holdren. Use the search function here on ATS and you will find more than enough info.