It looks like you're using an Ad Blocker.
Please white-list or disable AboveTopSecret.com in your ad-blocking tool.
Some features of ATS will be disabled while you continue to use an ad-blocker.
Aerosolized hydrogen peroxide demonstrates an excellent ability to neutralize methicillin-resistant Staphylococcus aureus (MRSA) environmental contamination, according to a new study. The neutralization appears to approach 100% and to last for weeks. It holds the promise of cost-effective infection control.
The key study, presented here yesterday at the 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy, was conducted at the Royal Hampshire County Hospital, Winchester, in the United Kingdom. In January 2007, a previously "clean" 28-bed surgical ward suffered an unexpected outbreak of MRSA in which 11 patients quickly became colonized.
Rotating sections of the ward were closed, and traditional decontamination cleaning took place. Moistened cotton swabs were used to gather samples from 29 standardized sites both before and after the hydrogen peroxide treatment and then at 1-week intervals for 4 weeks. Patients were screened at admission and discharge, and the staff was also screened; anyone found positive for MRSA was decolonized successfully.
The study found MRSA at 8 (27.6%) of 29 sites after traditional cleaning but at 1 (3.4%) of 29 sites after hydrogen peroxide treatment. The sites remained negative for MRSA on 3 successive weekly examinations, but on week 4, MRSA could be detected at 3 (10.3%) of 29 sites.
Study coauthor Jonathan Otter, PhD(c), works for Bioquell Ltd, the company that is developing commercial application of the technology, and participated in the study along with the hospital and government health agencies.
Mr. Otter believes that managing environmental contamination — in which the source of an infection has no direct physical contact with the patient who becomes infected but instead deposits the pathogen on a surface for third-party transmission — is an underappreciated part of infection control.
Mr. Otter explained that the decontamination process uses 30% hydrogen peroxide and a hot plate to create the vapor. Over the course of about 2 hours, the H 2O 2 settles on all exposed surfaces, and the highly reactive molecule destroys the pathogen. The reaction is not specific to MRSA, but that was the only pathogen measured in this study.
"In a previously presented study, a hospital in Connecticut instituted this technology for a period of 10 months throughout the entire facility, with a 53% reduction in colonization,"
A compound extracted from garlic is effective against even the most antibiotic-resistant strains of MRSA, the killer ‘hospital superbug’, and can cure patients with MRSA-infected wounds within weeks, according to new research by microbiologist Dr Ron Cutler of the University of East London (UEL).
In a paper to be published in the New Year, Dr Cutler, an expert in the antimicrobial properties of plant extracts, claims that allicin - a compound that occurs naturally in garlic – kills not only established varieties of MRSA, but also destroys the new generation of ‘super-superbugs’ that have evolved resistance to Vancomycin and Glycopeptides, the powerful antibiotics widely considered to be the last line of defence against MRSA.