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Originally posted by really
On topic, I see a lot of differing reports about the Ukraine. Some make it out to be something we should all truly worry about. Others make it out to be overplayed and nothing to worry about - normal flu stuff for this time of year there.
What does everyone think? Which is true?
ANCHORAGE, Alaska — Suspected swine flu is sweeping a traditional Eskimo whaling village on a remote Alaska island — prompting an urgent medical mission to deliver help.
"Diomede is probably the most isolated place in the United States right now," said David Head, a doctor involved in the effort. "We thought it would be better to go out there and just vaccinate people."
So many of the 130 residents of Diomede have been stricken with flu-like symptoms that the Alaska Army National Guard stepped in with a Black Hawk helicopter to transport a medical team from Nome 135 miles away, where Head is chief of staff at Norton Sound Health Corp.
Originally posted by seattletruth
reply to post by BigfootNZ
LOL I won't take offense.. but that idiot that made the video is me. I was just trying to point out ALL the symbolism I saw, maybe I went a little overboard. You can separate the wheat from the chaff, as I'm sure you did.
H1N1 Genetic Changes in RBD Raise Pandemic Concerns Recombinomics Commentary 19:09 November 8, 2009 Right now we know that many clinical specimens and viruses have been sent to one of the WHO collaborating centres for further study. We don't know the results of those studies, and it will probably take a couple of days for the full analysis of those viruses to be available. The above comments are from Thursday's WHO press conference and raise concerns that the sequences from Ukraine (see map) have small changes which may include receptor binding domain changes. Several such changes have been seen in previously published sequences and position 225 has been of concern. That position was linked to the establishment of amantadine resistance in seasonal H3N2 and raises concerns that such a change in swine H1N1 could make the virus more virulent. In seasonal flu, the change was D225N, and that change is in at least three swine flu sequences, including two from fatal cases in San Paulo, Brazil collected in August (see list here). The same position has also changed to D225G, which was also found in other fatal cases in San Paulo, Brazil. It is also in more recent (September) isolates from China (see list here). The new polymorphism most widely reported in sequences in Genbank is D225E, which is common in recent sequences from Italy (see list here). Thus, similar changes in sequences from Ukraine would be of most interest, and such changes have not been ruled out by WHO statements thus far. The release of these sequences from Ukraine is now overdue, and these delays increase pandemic concerns.
Originally posted by waterdoctor
reply to post by really
I would think that it would depend on how much work the lab has on the counter top. If they did not have a backlog of samples and worked 24/7 on it I would think that a good lab should be able to turn the sample around in 48 to 72 hours. That is a SWAG on my part as the only work that I did with DNA/RNA extraction was 30 years ago in the dark ages.
I think you are confused (on multiple counts). Laurie Garret was talking about E627K on PB2, which was reportd in the Netherlands as indicated in this Recombinomics commentray www.recombinomics.com...
It was also reported earlier in Shanghai, as indicated in this commentary www.recombinomics.com...
These are the only reported examples (no other pandemic H1N1 sequences at Genbank have this change). However, on youtube the responder on stage was actually talking about another gene, PB1-F2, which hasn't been found in any swine pandemic H1N1. The above is the current status of E627K on PB2 and the absence of PB1-F2 in pandemic H1N1.
Henry L. Niman, Ph.D. President, Founder Recombinomics, Inc.
Originally posted by CINY8
This article from the AP is not directly related to the Ukrainian situation, but it is interesting nonetheless.
ANCHORAGE, Alaska — Suspected swine flu is sweeping a traditional Eskimo whaling village on a remote Alaska island — prompting an urgent medical mission to deliver help.
"Diomede is probably the most isolated place in the United States right now," said David Head, a doctor involved in the effort. "We thought it would be better to go out there and just vaccinate people."
So many of the 130 residents of Diomede have been stricken with flu-like symptoms that the Alaska Army National Guard stepped in with a Black Hawk helicopter to transport a medical team from Nome 135 miles away, where Head is chief of staff at Norton Sound Health Corp.
www.foxnews.com...:s0:a16:g2:r2:c0.044989:b28762759:z10