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England's chief medical officer says further deaths from swine flu without underlying health problems cannot be ruled out but will be rare.
It follows the first death in the UK of a patient who was otherwise healthy. The victim lived in Essex and died in hospital on Friday.
Sir Liam Donaldson said it was a tragic case but people should not panic.
Fifteen people have now died in the UK after contracting swine flu - 13 in England and two in Scotland.
Sir Liam said that for the vast majority of people infected, the new flu virus had produced only mild symptoms.