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Influenza A/H1N1 virus has become more aggressive
"MEXICO CITY, May 15.
Influenza A/H1N1 virus mutated. As the radio «Mayak", said Director of the National Center for disease control in Mexico. According to officials, the changed virus can lead to new outbreaks of influenza, and more aggressive than the current one.
Similar cases have been registered in the United States and Canada. Now scientists have conducted a series of bioispytany. They will get a complete gene sequence of the virus and thereby confirm or refute these assumptions are dangerous.
Earlier, the Minister of Health of Mexico stated that the mutation of influenza virus is much more serious the AIDS virus..."
Use Google Translator to read in english...
Mom swap: Pig suckles baby tigers at zoo
Tigers and Pigs Swap Roles at Sri Racha Tiger Zoo
Why is it stupid:
Probable tiger-to-tiger transmission of avian influenza H5N1.
"During the second outbreak of avian influenza H5N1 in Thailand, probable horizontal transmission among tigers was demonstrated in the tiger zoo. Sequencing and phylogenetic analysis of those viruses showed no differences from the first isolate obtained in January 2004. This finding has implications for influenza virus epidemiology and pathogenicity in mammals."
I mean, good grief! Are they just begging for it or what?
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CDC swine flu report is ‘gross underestimate’
Published: May 16, 2009
Updated 7 hours ago
The Center for Disease Control’s official report of 4,714 cases of confirmed or probable swine flu could be underestimating the impact of the disease by around 45,000 cases, according to the deputy director of the CDC’s influenza division.
In a press conference yesterday, Dr. Daniel Jernigan took note of the difficulty in estimating how many Americans are infected with either seasonal or novel influenza(like swine flu) at any given time. “With the amount of activity we are seeing now, it is a little hard to know what that means in terms of making an estimate of the total number of people with flu out in the community.” However, when asked how many actual cases of influenza might currently exist nationwide, Jernigan acknowledged that the CDC numbers represented a gross underestimate. He told journalists, “if I had to make an estimate, I would say…probably upwards of maybe 100,000.”
Although up to 30 million Americans come down with seasonal influenza annually (7-10 percent), more than two dozen states are reporting unusually high levels of flu-like illness at a time of year when the respiratory disease usually disappears, health officials reported yesterday.
According to the CDC’s weekly H1N1 flu update, “about half of all influenza viruses being detected are novel H1N1 viruses.” The rise in both types of influenza implies that swine flu has a significant role in the spread of seasonal flu, as well. If Jernigan’s estimate of 100,000 cases of influenza is accurate, there could be more than 50,000 cases of swine flu in the U.S. “We would be expecting to see the season to be slowing down or almost completely stopped. We know the outbreak is not localized but is spreading and appears to be expanding throughout the United States. This is an ongoing public health threat,” Jernigan declared.
Influenza A(H1N1) - update 31
17 May 2009 -- As of 06:00 GMT, 17 May 2009, 39 countries have officially reported 8480 cases of influenza A(H1N1) infection.
Mexico has reported 2895 laboratory confirmed human cases of infection, including 66 deaths. The United States has reported 4714 laboratory confirmed human cases, including four deaths. Canada has reported 496 laboratory confirmed human cases, including one death. Costa Rica has reported nine laboratory confirmed human cases, including one death.
The following countries have reported laboratory confirmed cases with no deaths - Argentina (1), Australia (1), Austria (1), Belgium (4), Brazil (8), China (5), Colombia (11), Cuba (3), Denmark (1), Ecuador (1), El Salvador (4), Finland (2), France (14), Germany (14), Guatemala (3), India (1), Ireland (1), Israel (7), Italy (9), Japan (7), Malaysia (2), Netherlands (3), New Zealand (9), Norway (2), Panama (54), Peru (1), Poland (1), Portugal (1), Republic of Korea (3), Spain (103), Sweden (3), Switzerland (1), Thailand (2), Turkey (1), and the United Kingdom (82).
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Japan confirms 93 swine flu cases
KOBE, Japan (AFP) – Japan's number of confirmed swine flu cases soared to 93 at the weekend, officials said late Sunday, amid fears hundreds more are already infected in the country's crowded cities.
Most of the infections were reported among high school and college students in and around the western cities of Kobe and Osaka, where authorities ordered more than 1,000 schools and kindergartens to stay shut on Monday.
The island nation until Friday thought it had kept the virus at bay, after detecting four people who tested positive when they flew in from North America and immediately quarantining them along with about 50 fellow passengers.
But since the government Saturday confirmed the first domestic case, a 17-year-old male Kobe student who had not been overseas, the number of confirmed infections has risen quickly in the two urban areas.
Late Sunday officials in Hyogo prefecture, which includes Kobe, told AFP 53 cases had been confirmed, while Osaka prefecture reported 36, raising the national toll to 93, including the four overseas infections.
Originally posted by Hx3_1963
From posts a couple of days ago...
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Mexico detected a mutation of the H1N1 virus and warns has aggressiveness
May 13 09 - Mexico City
Just when the Mexican Government was attempting to convey an image of calm did what many experts had already predicted, the virus Muto, increasing the possibility of new outbreaks of influenza. Health authorities in Mexico, United States and Canada have found what could be a new version or a mutation of the influenza virus A (H1N1), and not out at the moment that is more aggressive than those currently circulating in the world.
"We have cases where immunofluorescence says is A, but does not tell us what subtype. Today we have cases like this, and this case is United States and Canada have such cases, revealed to the international media director general of the National Center of Epidemiological Surveillance and Disease Control (Cenavece), Miguel Angel Lezana.
The director of Cenavece did not rule out that this new version of the virus is more aggressive than currently circulating. "It is a possibility, the only way to know this is a series of bioassays, and the complete sequence of the gene of the virus, something in which he has been working, 'he explained.
In line, Health Minister Jose Angel Cordova said that the mutation of the human influenza virus is larger than that introduced the human immunodeficiency virus that causes AIDS. Cordova also presented the latest report on the evolution of this epidemic and reported that so far are 2446 cases of people who contracted the virus, 60 of whom were killed.
H1N1- Ultimate News on influenza A - bird flu, swine flu & avian flu alerts
H1N1 USA : more than 3000 cases: Swine H1N1 Outpaces Seasonal Flu In the United States
This movement of swine H1N1 into the human population is cause for concern. The increase over seasonal flu may be driven by the avian PB2 gene in the swine isolate. Position 627 is E, which favors growth at the higher body temperature of birds. Seasonal flu has a K at position 627, which allows for more rapid replication at a lower temperature, which is consistent with the internal temperature of a human nose in the winter.
The presence of avian PB2 may offer a selective advantage over the summer, when seasonal flu falls to barely detectable levels. However, the swine H1N1 that moves south in the upcoming months will be growing under colder conditions, which may favor the acquisition of E627K though reassortment or recombination. This change could create a more virulent H1N1 in the fall in the northern hemisphere.
Thus, the swine H1N1 may be launching a two virus strategy. The H1N1 with avian PB2 will dominate in the northern hemisphere over the summer, while the H1N1 in the southern hemisphere will acquire E627K and establish dominance during the winter months.
Thus, the spread of H1N1 is in high gear, as WHO debates if a swine H1N1 is a swine H1N1 and if a pandemic at phase 6 is really at phase 6.
Swine H1N1 doesn't read WHO press releases.
It just gains transmission efficiencies via homologous recombination
I also posted a link to something about "how it all started"...about some Wisconsin/Minnesota farming family that did something with sick pigs and chickens in a barn, but, can't find it at the moment...Hmmm...
PLease note the below supposition is my own, and not to be included in the quote- with my apologies for not separating the two correctly.
HX brings up an interesting nuance with this article. On the thread where we have discussed our illnesses, many people (including myself) have reference a LOWER body temp than is normal for a flu infection. I have been wondering about this and trying to contextualize the info relative to the outbreak. This info from HX helps me do just that- if H5N1 prefers a lower temp in the nose, and if the new strain(s) of H1N1 have mutations that in any way mimic the need for a cooler temp- perhaps those very mutations in addition to an avian reassortment could be what he have seen in individual descriptions by members. If this is the case, the bugs either thrive at lower temps (to avoid the fever that would ostensibly kill them), or they possses the mutation that allows them to lower a human's homeostatic temp, thus gaining a foot hold for invection. This is a hypothesis, and I welcome and and all feedback.
Great post HX.
[edit on 5/15/2009 by Hx3_1963]
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Update On Swine Flu (Influenza A H1N1) Infections - California and Texas, April 2009
April 26th 2009 01:00 AM
Secuence of artificial hibridization of new virus called “New Swine Influenza” done in the General Health Laboratorios, Trípoli, Lybia. (Ibn Hayan Project) in June/2008.
1) Live Simple (In Tissue Culture) Human Influenza.(H3N2) (Source Bragstad)
2) Live Simple ( In TC.) Aviar influenza (H5N1) (Source Viseshakul)
3) Live Simple (In TC ) Swine Influenza.(H1N1) (Source Sakamoto)
Methods. (Annex 002 detailed)
Low magnetic field bio-reactor in human tissue culture.
(H3N2)Segment PB2 (Transcriptase Bind)
(H5N1) Segment HA (Haemagglutinin)
(H1N1) Segment M2
The hybrid strain “Al Najem” 0281. was selected.
Packed in desodorant spray cans .
Path of fedayeens with “Al Najem” virus : Trípoli --Panama--Mexico City – El Paso –San Francisco-
(Ad libitum) (Feb./2009)
(Contact e-mail to Ali Suleiman : email@example.com)
Comm. Send in Panama City.
Anonymous (not verified) | 04/30/09 | 13:44 PM
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Another difference between eukaryotes and prokaryotes is mRNA transport. Because eukaryotic transcription and translation is compartmentally separated, eukaryotic mRNAs must be exported from the nucleus to the cytoplasm. Mature mRNAs are recognized by their processed modifications and then exported through the nuclear pore. In neurons mRNA must be transported from the soma to the dendrites where local translation occurs in response to external stimuli. Many messages are marked with so-called "zip codes" which targets their transport to a specific location.
Monocistronic versus polycistronic mRNA
An mRNA molecule is said to be monocistronic when it contains the genetic information to translate only a single protein. This is the case for most of the eukaryotic mRNAs. On the other hand, polycistronic mRNA carries the information of several genes, which are translated into several proteins. These proteins usually have a related function and are grouped and regulated together in an operon. Most of the mRNA found in bacteria and archea are polycistronic. Dicistronic is the term used to describe a mRNA that encodes only two proteins.
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AR Officials Investigate Possible Swine Flu Death
posted 05/17/09 1:53 pm
Little Rock - The Pulaski County Coroner’s office tells Channel 7 news they are investigating the death of a man as a possible swine flu fatality. Officials say they have not confirmed the exact cause of the man’s death, yet, but they are taking the necessary steps to determine if it is indeed a result of the H1N1 virus.
State health officials reported Friday there are at least six cases of swine flu here in Arkansas. That includes four National Guard airmen visiting from Nevada and New Jersey, a school-aged girl in Lawrence County, and a case in Saline County.
Anne Wright is the communications director for the Arkansas Department of Health. She says that, at this point, they are not confirming the cause of death. But if it is determined to be swine flu, the department will launch an investigation into how the man could have contracted the virus and if he he could have passed the disease onto others.
Wright says even if it is confirmed as a swine flu death, there is no reason for Arkansans to panic and that it could be an isolated incident.
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New York Reports Its First Swine Flu Death
An assistant principal at a New York City public school died of complications from swine flu in an intensive care unit of a Queens hospital on Sunday night, the first death in New York State of the flu strain that has swept across much of the world since it was first identified in April.
Hours before the death of the assistant principal, Mitchell Wiener, city officials announced that five more Queens schools had closed.
On Friday, Dr. Daniel Jernigan, head of flu epidemiology for the federal Centers for Disease Control and Prevention, said there had been 173 hospitalizations and 5 deaths reported to the agency. But he emphasized that most cases in the United States — possibly “upwards of 100,000” — were mild.
In Japan, the number of swine flu cases soared over the weekend, and authorities closed more than 1,000 schools and kindergartens .
Mr. Wiener’s death, which came five days after he entered the hospital and three days after his school, Intermediate School 238 in Hollis, Queens, was shut down by health officials, raised the level of concern among the public, especially parents, but health officials played down the significance of the death to public policy.
Japan closes 2,000 schools as swine flu spreads
11 mins ago
KOBE, Japan (AFP) – Japan has confirmed 129 swine flu cases and shuttered more than 2,000 schools and kindergartens in a bid to slow the spread of the virus that may already have infected hundreds.