USDA website article from 2004 describes reverse genetics to make bird/human/swine flu, page 1
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Topic started on 3-5-2009 @ 10:23 PM by ExPostFacto
www.ars.usda.gov...


...Veterinary medical officers Jürgen Richt and Kelly Lager of the ARS National Animal Disease Center (NADC) in Ames, Iowa, are using a process called reverse genetics to gain insight into an alarming development: rapid spread throughout North America of a swine flu type that contains gene segments from birds and humans as well as from pigs.

The researchers, who work in NADC's Virus and Prion Diseases of Livestock Research Unit, are using reverse genetics to create new flu viruses in efforts to explore individual components of the virus. The hope is that these components can in turn be exploited by vaccines....

...What made reverse genetics attractive for exploring the new swine flu strains is that manipulations commonly done on DNA cannot be performed with RNA....

..."Current human and swine vaccines are inactivated vaccines that vary in efficacy, depending on the match of the vaccine with influenza virus strains circulating in the susceptible population," says Richt. "Modified-live-virus vaccines generated through reverse genetics can stimulate a better, broader immune response than killed-virus vaccines."...

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