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The first case, a 10-year-old DOD dependent, was identified in a trial to evaluate a novel influenza diagnostic. On 1 April, a swab sample from the patient was tested on the diagnostic platform. The result suggested an influenza A but subtype negative virus. Our screening questionnaire deemed the patient at low-risk for an avian influenza infection. Per the study protocol, a second specimen was sent to a third-party lab in Wisconsin. This laboratory, along with the state laboratory, confirmed the influenza A/un-typed finding. The specimen and an isolated virus were then sent to the CDC for confirmation. The CDC determined the virus was an influenza A/swine/H1N1.
The second case, a 9-year-old female from Brawley, California, was sampled in the collaborative study with the CDC’s Border Infectious Disease Surveillance Project. What was thought to be a routine specimen was sent to our laboratory the first week in April. Our initial testing demonstrated an influenza A/untyped virus. Further testing on the Ibis T5000 platform, which infers H and N types from multiple genomic signatures, suggested an influenza A/swine/H1 virus. [Although most tests rely on known DNA sequence or antibodies to identify influenza isolates, the Ibis T5000 has a mass spectrometer and can identify unknown subtypes.] This was right about the time we received word from CDC about the first case. At that point we knew we were onto something significant. The CDC subsequently confirmed an influenza A/swine/H1N1 virus
One sailor on the ship was confirmed to have the virus, also called H1N1, and 50 other crew members are exhibiting flu-like symptoms, said Cmdr. Cappy Surette, a Navy spokesman at the Pentagon. It was not immediately clear if the 50 sailors have been confirmed as having a “novel virus” such as H1NI, as opposed to seasonal flu.
DoD-GEIS Respiratory Illness Surveillance Projects at Naval Health Research Center, San Diego
The Naval Health Research Center (NHRC) serves as the Navy node for the Department of Defense Global Emerging Infectious Disease Surveillance and Response System. NHRC conducts laboratory-based epidemiological studies of viral and bacterial pathogens at basic training (recruit) centers, military medical facilities, shipboard, and in deployed units.
The Naval Health Research Center (NHRC) serves as the Navy node for the Department of Defense Global Emerging Infectious Disease Surveillance and Response System. www.geis.fhp.osd.mil...
Originally posted by Hx3_1963
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Malaysian being tested for Influenza A
The U.S. Navy says it has canceled the deployment of a ship and ordered its entire crew to be treated with anti-viral drugs after a crew member's illness was confirmed as swine flu.