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The area in question - the right parietal lobe - is responsible for defining "Me," said researcher Brick Johnstone of Missouri University. It generates self-criticism, he said, and guides us through physical and social terrains by constantly updating our self-knowledge: my hand, my cocktail, my witty conversation skills, my new love interest ... People with less active Me-Definers are more likely to lead spiritual lives, reports the study in the current issue of the journal Zygon.