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ScienceDaily (Oct. 31, 2008) — In the largest ever genetic study of male to female transsexuals Australian researchers have found a significant genetic link between gender identity and a gene involved in testosterone action.
DNA samples were collected from 112 male to female transsexuals and researchers compared genetic differences with non transsexuals.
The researchers discovered that male to female transsexuals were more likely to have a longer version of a gene which is known to modify the action of the sex hormone testosterone.
"We think that these genetic differences might reduce testosterone action and under masculinise the brain during fetal development." said researcher Lauren Hare.