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SYDNEY (AFP) - An Australian girl spontaneously switched blood groups and adopted her donor's immune system following a liver transplant in the first known case of its type, doctors treating her said Thursday.
Demi-Lee Brennan was aged nine and seriously ill with liver failure when she received the transplant, doctors at a top Sydney children's hospital told AFP.
In the first study at Stanford University, a man who received his brother's kidney has gone for two years without drugs after his doctors tweaked his immune system with irradiation and antibody treatments.
He then received an infusion of his brother's blood cells. This combined treatment created a kind of "peacekeeping" immune cell, which appeared able to avert the attack on the foreign organ.
The second study was conducted at Massachusetts General Hospital.
Five patients were given treatment that partially destroyed their bone marrow and with it the white blood cells which cause rejection.
This bone marrow was then replaced with a bone marrow graft from the donor, and the kidney followed.
One of the five rejected the kidney, but the other four have so far been able to live with normal kidney function and without drugs - the longest for over five years.
Originally posted by NGC2736
There is an often told story in my wife's family about a nephew who was listed as an A+ in early childhood. It seems it was on his records. Then later, as an adult, he went in to have some work done, and they said he was O+.
I always figured there was just a mix-up of some sort. But considering how strange her family is, and now this, I'm about to become a believer.