posted on Nov, 15 2007 @ 08:30 PM
Well Dale (great username by the way!), much of it would depend on how you originally acquired the infection. Most cases that I know of involving
adult Osteomyelitis were initially caused by chronic bacterial infections from Staphylococcus aureus or Streptococcus pyogenes. Basically what
happens is that the bacterium will enter the subject through some sort of open wound stimulating Leukocyte production in the Thymus and Lymphatic
system. These Leukocyte cells will begin to strip off the Periosteum that surrounds the outer layer of the bone (when the bacterial infection runs
deep) and promote the growth of Involucrum bone tissue to try and repair the damaged surface. If left untreated it could eventually lead to far
greater problems with bone density and deformity; not that I'm trying to say this will happen to you.
There are several common medications that are used to treat it and I would be curious as to what they prescribed to you during your previous
infection. Maybe they have already tried one of these:
Nafcillin- initially given to most patients because by the time they progress to Osteomyelitis they are generally resistant to penicillin G
Streptococcal and/or staphylococcal bacterium.
Cefazolin- This is essentially a organic/synthetic Cephalosporin that prohibits bacterial cell wall synthesis and thus will act to inhibit bacterial
Vancomycin- usually only useful against gram-positive bacterial species like Enterococcus, but has been noted to help stop some forms of antibacterial
There are others of couse like Erythema, Linezolid, Ceftriaxone, etc., but it would take forever to go through them all. Since you mentioned that the
VA Physician told you that the infection has not completely gone I would venture a speculative guess that it may be chronic and could require further
treatment with antibiotics as they are usually continued for months with an infection involving bacteria found in the order of Lactobacillales. In
lieu of this, one thing that may sound rather gross, but could help, would be a dual treatment with antibiotics and maggots. The antibiotics would
help the infection from continuing to spread, and the maggots would literally eat away at any necrotic tissue remaining post-infection. Either way, I
would definitely consult your VA Physician or another Physician if the first doesn't help.