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Handling uncooperative victims
One of the elements that separates a drill from a real-life situation is dealing with panicked or uncooperative victims.
In a real attack, the perpetrators may be among the victims, or that some of the victims may be in possession of contraband, or of evidence that might help law enforcement in solving the crime.
Another consideration is that some of the perpetrator victims might refuse to go through decon because this would result in discovery of the contraband they may be hiding.
For example, a person with explosives strapped to his or her body, under their clothing, would likely not be so willing to take it off. Such a victim might try to escape, and need to be restrained for decon.