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The European Space Agency (ESA) on Tuesday called for applications for one of the most demanding human experiments in space history: a simulated trip to Mars in which six "astronauts" will spend 17 months in an isolation tank on Earth.
Their spaceship will comprise a series of interlocked modules in an research institute in Moscow, and once the doors are closed tight, the volunteers will be cut off from all contact with the outside world except by a delayed radio link.