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Genetically-Engineered Cattle May Defeat Prions

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posted on Jan, 2 2007 @ 04:18 PM
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(from ATSNN)

A team of scientists have bred cattle that lack the gene that creates the misshapen prions that cause 'Mad Cow Disease." One misshapen prion is thought to be sufficient to cause normal prions to turn bad and cause the brain wasting disease. Currently, cattle are being injected with bovine spongiform encephalopathy (BSE) to see if they are indeed immune to the disease.
 



www.theaustralian.news.com.au
SCIENTISTS have genetically engineered a dozen cows to be free from the proteins that cause mad cow disease, a breakthrough that may make the animals immune to the brain-wasting disease.

An international team of researchers from the US and Japan say they have "knocked out" the gene responsible for making the proteins, called prions.

The disease did not take hold when brain tissue from two of the genetically engineered cows was exposed to bad prions in the laboratory, they said.

Please visit the link provided for the complete story.


BSE has had a tragic impact on both the beef industry and those who have contracted the disease. To date, more than 150 people have died from BSE, contracted by eating infected beef.

If this breakthrough proves truly effective, it could not only relieve the beef industry of this problem, but make the food supply that much safer for humans.

Related News Links:
www.sciencedaily.com
www.pbs.org
www.mass.gov
www.sciencenews.org

Related AboveTopSecret.com Discussion Threads:
Mad Cow disease in US!
Is Biotech Creating New Incurable Diseases Accidentally?
NEWS: "Mad Cow-like" Prions Possible in Sheep Milk?
POLITICS: Mad Cow-causing Prions Found in All Organs

[edit on 2/1/2007 by Mirthful Me]

[edit on 2-1-2007 by DontTreadOnMe]




posted on Jan, 2 2007 @ 05:16 PM
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Good catch.


I filed this one - didn't get to it - but here are a few quick comments.

FYI

Human drugs and vaccines are manufactured using U.S. cattle and cattle products.

Continued profitability, and avoiding liability lawsuits, depends on convincing people that the process is safe, always was safe, and always will be safe - that prion diseases like Mad Cow are "genetic," only affect the brain, and are NOT a problem in the USA. All systems go.


...U.S. herd an ideal resource for companies that extract blood and other products from cattle for use in human pharmaceuticals.

...it may not be necessary for Hematech to use prion-free cattle as it strives to make potent, disease-killing antibodies in cattle for use in humans with life-threatening infections.

Misfolded prion proteins are blamed for BSE and other, similar brain diseases. It is known that certain genetic variations make animals more susceptible to the diseases.




Sorry. It's NOT safe.

Drug and vaccine manufacturing processes don't just spread infectious prions - standard manufacturing processes create new infectious prion strains.

This is common knowledge in the scientific world. It is the reason for running a mega-billion dollar fifty-year marketing campaign to say prions don't exist. It is the reason the FBI destroyed Linus Pauling's reputation in the early 1950's - and it's the reason Stanley Prusiner had to wait 20 years to get a Nobel Peace Prize for 'discovering' infectious prions.

Everyone who knows anything about proteins knows they misfold and create infectious prions. Everyone who knows anything about the pharmaceutical industry knows they've been targeting proteins since Pauling discovered the actin protein's "a" and "b" configurations in 1950 - and the processes and products have been creating new prion strains since then. And everyone knows that the chronic disease epidemic results from infectious prions created by industry. They just don't talk about it publicly - or they'd be destroyed financially or professionally, or fatally mugged, or charged with treason.

It's NOT safe to use animals products to create drugs - and it's common scientific knowledge.

But these processes continue to be used, and the products remain on the market because the standard analysis says the 'benefits' outweigh the 'risks.'

But the standard "risk-benefit analysis" is NOT scientific or medical - it's economic. And it's dead wrong - as evidenced by the rising costs of Social Security, and health related unemployment and disability payouts.

Prion-related diseases usually take decades to cause symptoms; so the big boyz bet on everyone dying before they got too sick to work. But guess what? It didn't happen that way. Now prion-related diseases are pandemic and still spreading, and killing every national economy because they do not kill their victims, they just render them unproductive.

So when all the nation-states go broke supporting all their prion-infected disabled citizens, who here thinks the corporate-states are in position and ready to run with the ball?



Also see:

Mad Cow Madness

Prion Contaminated Vaccines



posted on Jan, 2 2007 @ 08:10 PM
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An interesting tidbit:

There is a campaign to narrow the definition of "prion" to include only one particular protein - a 33–35 kD protein - coded for by one specific gene on the short arm of chromosome 20.

In fact however, the world is full of prions...

Here are a few quick definitions that have not yet been censored:



Prion: A disease-causing agent that is neither bacterial nor fungal nor viral and contains no genetic material. A prion is a protein that occurs normally in a harmless form. By folding into an aberrant shape, the normal prion turns into a rogue agent. It then coopts other normal prions to become rogue prions.

Prions have been held responsible for a number of degenerative brain diseases, including scrapie (a fatal disease of sheep and goats), mad cow disease, Creutzfeldt-Jacob disease, fatal familial insomnia, kuru, an unusual form of hereditary dementia known as Gertsmann-Straeussler-Scheinker disease, and possibly some cases of Alzheimer's disease.

Dr. Stanley B. Prusiner received the 1997 Nobel Prize in Physiology or Medicine for his discovery of prions. See also: Prusiner, Stanley B..

***

Protein infectious agent associated with several neurological diseases (scrapie; kuru; Creutzfeld-Jakob syndrome; Alzheimer's disease). Each disease has a different prion.

***

prion (plural prions)

1. The etiologic agent of transmissible spongiform encephalopathies. The only self-replicating cause of disease known to lack nucleic acids.
2. A self-propagating alternative conformer of any protein.


***

cancerweb.ncl.ac.uk...]prion - The word, for proteinaceous infectious agent, was coined in 1982 by neurologist Stanley Prusiner as part of a hypothesis regarding ailments bearing aetiologic resemblance to those caused by slow viruses (for instance, kuru). The hypothesis has been borne out by investigation. Prions are now believed responsible for several transmissible neurodegenerative diseases




posted on Jan, 2 2007 @ 08:25 PM
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When I came to this article it sound it to good to be true, specially with all the denial about prions before.

Now this people wants to look like champions of mankind and start telling that it may be a solution.

The pharmaceutical empire business is to make money and profits no to find cures.



posted on Jan, 2 2007 @ 08:39 PM
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Originally posted by marg6043

The pharmaceutical empire business is to make money and profits no to find cures.




No kidding.

Plus - they're pushing "short term gain, for long term pain" - and not even telling us that's the deal.



Their so-called 'treatments' cause worse disease - and knock people over before their time.

Just watch - they're going to convince people that's it's "better" to have euthanasia - and get rid of the evidence and burden, all at the same time.

Do you see how it works? They infect people, but no one knows they're infected or where it started because the symptoms don't show up for decades, and pop up a little differently from person to the next. So the rich guyz get 20-30 years hard labor out of us suckers - and when we get too sick to work, BAM! Euthanasia. For our own good.

Sure.


.



posted on Jan, 3 2007 @ 12:21 AM
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Said it in the science thread, and I will say it here...
Mad cow, about 10 years ago when I first remember hearing about it in England, was caused by making canibal cows. Or slopping cow braind to animals that are not supposed to be meat eating, etc.

Instead of properly caring for the animal, lets mutate them and keep feeding them a sick diet...sounds great and promising those in charge of science.

Make dieseases from carelessness and greed, and then mutate them so that we will now get diesease from needing to adjust to mutated animals, and then make money for the cures they try to come out with, then money for the funerals, etc.

Life goes on as normal on this hillarious, silly little planet called earth.


Peace

dAlen




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