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Philip Bouhler and Karl Brandt
Bouhler born in Munich, September 02, 1899 and Karl Brandt, Hitler's personal physician, are credited with the foundation of the T-4 movement. Named after the address of the headquarters at Tiergarten 4, Bouhler, who had come up through the ranks and proved himself as a party loyalist went on to streamline the T-4 program into a mass extermination effort so effective against the mentally infirm that he would later with his cohorts be asked to do the same for the mass extermination of the Jews.
The Musical Instrument Museum was formerly the site of Tiergartenstrasse 4, the headquarters of the Nazi regime's "euthanasia" program (in fact a program of mass murder of disabled people and others deemed "worthless" by the Nazis), which was known by the code name T4 in reference to this address
Originally posted by Crakeur
On October 15, 1918, shortly before the end of the war, Hitler was admitted to a field hospital, temporarily blinded by a poison gas attack. The English psychologist David Lewis and Bernhard Horstmann indicate the blindness may have been the result of a hysteria. Hitler later said it was during this experience that he became convinced the purpose of his life was to "save Germany". Some scholars, notably Lucy Dawidowicz, argue that an intention to mass murder Europe's Jews was fully formed in Hitler's mind at this time, though he probably hadn't thought through how it could be done.
taken from wikipedia.