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Dopamine receptor vaccine?

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posted on Jul, 1 2006 @ 11:57 PM
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I'm looking for information regarding a claim that scientists have developed a vaccine that attacks dopamine opioid system receptors in the brain. The claim is that this vaccine would obliterate the receptors in the brain the receive endorphins known as opioid peptides as well as blocking foreign opioid "look alike" chemicals such as heroin, coc aine, and nicotine. This information was on Alex Jons' new video "Terrorstorm."

I've been searching on this for some time and haven't found anything other than the vaccines developed to directly target foreign opioid as drug abuse treatment. If lacking any evidence, please post your thoughts.

My first thought after "I want to find evidence" was that this vaccine could be used to turn us all into emotionless robots. Perhaps they would start prescribing the vaccine to people who have severe drug abuse problems, maybe the criminally insane. Marketing for the vaccine could be as simple as giving the vaccine to newborns with the promise that the child will never have a drug abuse problem.




posted on Jul, 2 2006 @ 01:05 AM
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Hrmm, I searched as well, through my own medical journal search engines like PubMed, my hard copies of journals, and google, too, and came up with nothing.

There's one main problem you would run into with something like this. See, the reason you have massive withdrawals from heroin and related drugs, and also why you constantly need to increase the dosage, is that when dopamine receptors on neurons are stimulated to active the chemical signal, they also stimulate the creationg of more dopamine receptors. This is how your body manages to use a good deal of the dopamine released by your neurons. However, once the dopamine levels drop off, you are left with just a few empty receptors, which will be destroyed, leaving only the primary receptors.

The problem occurs, however, when you introduce an antagonist. Antagonists mimic the effect of a chemical; heroin acts as an antagonist for dopamine, if I'm not mistaken. This huge increase in dopamine antagonists causes the creation on many, many more receptors, which eventually go unfilled, leading to the post-high crash. Thus, any vaccine that would act in a similar nature, that is, filling the gaps in dopamine receptors, would cause the same crash effect, albeit perhaps without the addiction.

So, essentially, this may not be a true vaccine, rather more of a safe alternative to methadone for heroin addicts to wean themselves off of drugs with. That is, if it exists.

Mariella



posted on Jul, 2 2006 @ 04:24 AM
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I think what you are talking about is Naltrexone which blockades the opioid receptors ini your brain.

It is used to counteract opiates as well as aid in treatment of alcoholism. It is not a new drug, but a new form of it as an injection that lasts for a longer time has been recently introduced.



 
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