Originally posted by mattison0922
I'm going to have to ask for further elaboration. I think I understand what you're trying to say. Are you stating that simply because a DNA sequence
is inserted, doesn't mean we know what the protein will end up like. I think you bring the prions iinto it to perhaps highlight the idea, that a
prion is simply a different energy minima relative to a different structure. And I think what you're trying to say, is that while we know the DNA
sequence codes for a certain protein, we don't necessarily know what energy minima this protein will adopt in a potentially radically different
cellular context. Does this about sum it up?
Yes, if prions emerge through the folding of mature proteins, wouldn't an unfinished one be even more susceptible to deformation?
Let's say that this protein does adopt the harmful configuration in this new cellular context. Part of the trick with crystal growth in proteins, is
finding the right conditions under which the protein will crystallize. This may or may not resemble cellular conditions. If it adopts this harmful
minima only under these conditions, it may not be easy to find.
Sure, but if your lab rats lose a thrid of their weight when being fed a certain GM crop, you know you're doing something wrong. Tests like these
were carried out in Australia, iirc, the mechanism remains unknown though.
Anyways, there are known examples of outright bugs in GMOs, nothing is being done about them, as the case of the growth hormone so clearly
demonstrates, i know of noother industry that can get away with tainted products as easily (well, perhaps the Pharma industry)
