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"It is quite possible," Ferry said, "that this could be the first metabolic cycle."
[the cycle is]
in the presence of minerals containing iron sulfides, acetate could have been catalytically converted to a sulfur-containing derivative called an acetate thioester. Attached to the mineral surface, a "protocell" containing primitive forms of these two enzymes [Pta ("phosphotransacetylase") and Ack ("acetate kinase.") ] could then have generated biochemical energy by converting this derivative back to acetate. Excreting acetate would have completed the cycle.
pta and ack are transcribed as an approximately 2.4-kb polycistronic message and that the regulation of enzyme synthesis occurs at the mRNA level
"This long-standing debate between the heterotrophic and chemotrophic theories," House continued, "revolved around carbon fixation." The new thermodynamic theory inverts the focus, Ferry said. "All these pathways evolved first to make energy. Afterwards, they evolved to fix carbon. These ideas suggest a totally new perspective. It's truly a quantum leap -- a milestone."
Originally posted by Nygdan
"It is quite possible," Ferry said, "that this could be the first metabolic cycle."
[the cycle is]
in the presence of minerals containing iron sulfides, acetate could have been catalytically converted to a sulfur-containing derivative called an acetate thioester. Attached to the mineral surface, a "protocell" containing primitive forms of these two enzymes [Pta ("phosphotransacetylase") and Ack ("acetate kinase.") ] could then have generated biochemical energy by converting this derivative back to acetate. Excreting acetate would have completed the cycle.
The paper should be interesting. I am not clear on where they are saying this fits in. It requires two complex proteins and vinegar. Its occuring on a mineral surface, so it seems like its not expected to occur within a 'protocell' (but say one that lacks steady metabolic activity).
It seems like it implies that genetics existed before metabolism,
Here is a paper on the genetic regulation of those proteins in a member of the same genus as the creature in the above study
jb.asm.org...
pta and ack are transcribed as an approximately 2.4-kb polycistronic message and that the regulation of enzyme synthesis occurs at the mRNA level
interesting. I am just wondering what we'd expect of something that is so primitive. Polycistronic mRNA processing isn't unusual, but it might hint at some sort of support for an RNA world. Messenger RNA that acts as a go between between protein strucutre and DNA structure doesn't seem to clash with this idea. I wonder if there is something unusual about these proteins that would make mRNA likely to form around them and reproduce them?
"This long-standing debate between the heterotrophic and chemotrophic theories," House continued, "revolved around carbon fixation." The new thermodynamic theory inverts the focus, Ferry said. "All these pathways evolved first to make energy. Afterwards, they evolved to fix carbon. These ideas suggest a totally new perspective. It's truly a quantum leap -- a milestone."
Originally posted by V Kaminski
Thanx mattison0922, I thought it a rather unusual article. A friend over at CSA (Canadian Space Agency) turned me on to it while I was hunting for "alternative uses for RADARSAT"...
seems some CSA and ESA scientists are really jazzed about a tentative proposal to get some of these little guys up on the ESA Columbus ISS module in the next decade or so and see if they can be coaxed to give methane as rocket fuel and to explore the outside chance their appetite for carbon monoxide can be applied to cracking waste respiratory carbon dioxide that (highly maintenace intensive) scrubbers and beds currently deal with.
I don't have a clue about their "Thermodynamic Genesis" theory tho'... 'bound to ruffle at least some feathers when it is more widely known.
Thanx again for replying and I'm glad you thought the article was worth reading,
Originally posted by mattison0922
I didn't get this impression... can you perhaps elaborate?
If these enzymes evolved separately, and were part of different systems, what's the selective pressure to arrange them in operons
what's the mechanism by which related genes are clustered into operons?
what's the mechanism whereby genes are clustered into 'translationally dependent cascades,' ie translation of a preliminary component in the pathway is necessary before later components can be tranlsated?
but again don't get your hopes up for this to become a "most viewed thread though.
Originally posted by sayswho
What about archebacteria? Isn’t it a protobacteria that preceded both eukaryotes and prokaryotes before plant life and animal life were separate life forms?
I have for some time assumed that the building blocks for RNA were either present in primitive that primordial soup which became the early oceans or arrived piggy back on some meteorite.
Would assumptions based upon this study obviate my position?
I have decided that if man insists upon a deity, its name must be Archae.