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Two men are in critical condition in a London hospital and four others are in serious condition after taking part in a clinical trial for a new drug.
One victim, whose head and neck were reported to have increased to three times normal size, was described by a friend as resembling "the Elephant Man."
The men were admitted late Monday to the intensive care unit from an independent medical research unit at Northwick Park Hospital after reacting badly to the drug, which is intended to treat chronic inflammatory conditions and leukemia.
Originally posted by bsl4doc
You're absolutely right. Your experience with a handful of poor doctors totally invalidates all doctor's abilities every where and forever.
Sheesh, some people.
Originally posted by suzy ryan
It's you who condemns every opinion of those who dare to disagree with ANY of your. I just don't see the need to sprook for the industry of drugs as they do far too good job of it as it is.
I don't know what's so bad about sharing the other side of 'medicine' when you so keenly come on tell everyone it's all, all good.
And these are the people most 'worship' and who now decide if a baby's life is 'worth' living....AAAHHHH!
Two men are in critical condition in a London hospital and four others are in serious condition...
Eight men had all volunteered to take part in the trial. Two were given a placebo and were unharmed.
...the drug, TGN1412, was an antibody developed by TeGenero of Wuerzburg, Germany.
TGN1412 bypasses the requirement for TCR signalling and activates T cells regardless of their TCR specificity.
TGN1412 is far advanced in pre-clinical development. It has shown unique ex vivo and in vivo T lymphocyte activating capacity and great therapeutic potential for a number of autoimmune/inflammatory and oncological diseases.
B cell chronic lymphocytic leukaemia (B-CLL)
Originally posted by FredT
Interesting that none of these side effects showed up in animal testing. You can get a paradoxical reaction to drug and they may act in the opposite way. bendryl is one such drug whee some will become hyper rather than sedate etc.
The men had been told by doctors they would not suffer any life-threatening illnesses.
Nav Modi, 24, whose bloated face and swollen chest led to the nickname “Elephant Man”, said he did not know how long he would live.
“It’s a really bizarre feeling when you discover you might be dead in a couple of years or even in a couple of months,” he said. “I feel like I’ve given away my life for £2,000.”
Originally posted by FredT
Interesting that none of these side effects showed up in animal testing.