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Worry is characterised by the question “What if...?”, says Dr Gillian Butler, clinical psychologist at Oxford''s Warneford Hospital. ‘It is about the risk or threat of something bad happening in the future and whether you could cope if it did. It can also be rather vague. Just a sense that something might go wrong, and not being sure what to do to prevent it.
Source: Do you worry yourself sick?
The role played by stress in the causation of cancer is so great that it would not be an exaggeration to say that 80% or more cancer cases have their immediate origin in some form of mental pressure or strain. Grief, distress, fear, worry and anger are emotions which have horrible effects on the body's functions. Researchers have discovered that these emotions cause the release of chemicals from the brain called neuropeptides. These potent compounds have a profound immune-suppresive action. Scientists have traced a pathway from the brain to the immune cells proving that negative emotions can stop the immune cells dead in their tracks. This results in part from the release of chemicals from nerve endings. Once this happens, harmful microbes or cancer cells can invade any tissue in the body.
Source: Eat Right or Die Young, Dr. Cass Igram, Literary Visions Inc., 1989
There are various types of neurotransmitters, which are usually specific to a certain type of nerve or function. Neuropeptides were the last to be discovered. They withdraw down a cascade creating other neuropeptides and other bioactive compounds that are specific to different systems. Thus a bioactive compound low down in the cascade of degeneration can be biologically active elsewhere in the body from where the originating neuropeptide was released. It is therefore possible that the degenerating cascade can influence all systems albeit at sequential points in time. Neuropeptides also influence cellular activity at the DNA level by altering gene structure to either increase or decrease gene expression.
Source: Neuropeptides