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1) Since 2012, multiple in-vitro studies have demonstrated that Ivermectin inhibits the replication
of many viruses, including influenza, Zika, Dengue and others (Mastrangelo et al.,
2012;Wagstaff et al., 2012;Tay et al., 2013;Götz et al., 2016;Varghese et al., 2016;Atkinson et
al., 2018;Lv et al., 2018;King et al., 2020;Yang et al., 2020).
2) Ivermectin inhibits SARS-CoV-2 replication and binding to host tissue via several observed
and proposed mechanisms (Caly et al., 2020b).
4) Ivermectin significantly diminishes viral load and protects against organ damage in multiple
animal models when infected with SARS-CoV-2 or similar coronaviruses (Arevalo et al.,
2020;de Melo et al., 2020).
5) Ivermectin prevents transmission and development of COVID-19 disease in those exposed to
infected patients (Behera et al., 2020;Bernigaud et al., 2020;Carvallo et al., 2020b;Elgazzar et
al., 2020;Hellwig and Maia, 2020;Shouman, 2020)