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"'Man With The Screaming Brain' is a story of greed, betrayal and revenge in the big, bad city," Campbell told CBR News by phone last week. "In this case, it's the city of Bravada, Bulgaria. It's sort of a sociological metaphor masquerading as a horror film. It's the struggle of a right-wing capitalist who has part of his brain removed and replaced by a former KGB operative in gypsy town. So, it's a strange combination of characters, but they have to make peace with each other and team-up to find the woman who killed them both, so it's a murder mystery at the same time."